Chromo domain-containing protein 1 (CHD1) is a 1468-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P32657.
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The mean pLDDT of this model is 69.9 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 21% |
| 70 to 90 | Confident: backbone generally right | 41% |
| 50 to 70 | Low: treat with caution | 12% |
| Below 50 | Very low: often disordered regions | 26% |
What pLDDT means and how to read it
ATP-dependent chromatin-remodeling factor which functions as substrate recognition component for the transcription regulatory histone acetylation (HAT) complex SAGA. Recognizes H3K4me. Acts in opposition to the FACT complex in regulating polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the pol I transcription termination step. Negatively regulates DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome
Monomer. Interacts with RTF1, SPT5 and with the FACT subunits POB3 and SPT16
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2XB0 | X-ray | 2.0 Å | X=1009-1274 |
| 3TED | X-ray | 2.0 Å | A=1006-1274 |
| 2H1E | X-ray | 2.2 Å | A/B=174-339 |
| 7TN2 | EM | 2.3 Å | W=118-1274 |
| 9N6H | EM | 2.54 Å | K=122-956 |
| 9N6I | EM | 2.61 Å | K/L=122-956 |
| 7NKX | EM | 2.9 Å | W=1-1468 |
| 9N6K | EM | 2.9 Å | K/L=122-1265 |
| 5J70 | X-ray | 2.96 Å | A/B=1006-1274 |
| 9GD3 | EM | 3.0 Å | T/W=1-1468 |
| 3MWY | X-ray | 3.7 Å | W=142-939 |
| 9R5S | EM | 3.8 Å | W=2-1468 |
| 9GD1 | EM | 4.0 Å | W=1-1468 |
| 9GD2 | EM | 4.2 Å | S/T/W=1-1468 |
| 6FTX | EM | 4.5 Å | W=175-1269 |
| 6G0L | EM | 4.5 Å | M/W=1-1468 |
| 5O9G | EM | 4.8 Å | W=1-1468 |
| 2DY7 | NMR | A=172-252 | |
| 2DY8 | NMR | A=279-347 |
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