Cyclin-dependent kinases regulatory subunit 2 (CKS2) is a 79-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P33552.
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The mean pLDDT of this model is 92.5 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 87% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function
Forms a homohexamer that can probably bind six kinase subunits
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6GU2 | X-ray | 2.0 Å | C=1-79 |
| 5LQF | X-ray | 2.06 Å | C/F=1-79 |
| 1CKS | X-ray | 2.1 Å | A/B/C=1-79 |
| 4Y72 | X-ray | 2.3 Å | C=1-79 |
| 5HQ0 | X-ray | 2.3 Å | C=1-79 |
| 6GU6 | X-ray | 2.33 Å | B=1-79 |
| 6GU3 | X-ray | 2.65 Å | C=1-79 |
| 4YC3 | X-ray | 2.7 Å | C=1-79 |
| 6GU4 | X-ray | 2.73 Å | C=1-79 |
| 6GU7 | X-ray | 2.75 Å | B/D/F/H=1-79 |
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