SET domain-containing protein 3 (SET3) is a 751-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P36124.
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The mean pLDDT of this model is 62.0 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 14% |
| 70 to 90 | Confident: backbone generally right | 30% |
| 50 to 70 | Low: treat with caution | 14% |
| Below 50 | Very low: often disordered regions | 42% |
What pLDDT means and how to read it
Histone reader that recognizes histone H3 di- or tri-methylated at 'Lys-4' and acts as part of large multiprotein complexes that modify and/or remodel chromatin to regulate transcription (PubMed:12434058, PubMed:23798402, PubMed:27697561). Required for both gene activation and repression (PubMed:12434058). Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis (PubMed:12434058). Required for the transcriptional activation of genes with high activity (PubMed:12434058)
Identified in the Set3C complex with HOS2, HST1, SNT1, SIF2, CPR1 and HOS4
Nucleus, Chromosome
Compare the prediction with experimentally determined structures of the same protein:
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