Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 (STT3) is a 718-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P39007.
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The mean pLDDT of this model is 88.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 65% |
| 70 to 90 | Confident: backbone generally right | 30% |
| 50 to 70 | Low: treat with caution | 2% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (PubMed:12359722). This subunit contains the active site and the acceptor peptide and…
Component of the oligosaccharyltransferase (OST) complex, which appears to exist in two assemblies comprising OST1, OST2, OST4, OST5, STT3, SWP1, WPB1, and either OST3 or OST6 (PubMed:10677492, PubMed:15831493, PubMed:15886282, PubMed:16096345, PubMed:16297388, PubMed:29301962, PubMed:9405463, PubMed:9435788). OST assembly occurs through the formation of 3 subcomplexes. Subcomplex 1 contains…
Endoplasmic reticulum membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8AGE | EM | 2.8 Å | A=1-718 |
| 8AGB | EM | 3.0 Å | A=1-718 |
| 8AGC | EM | 3.1 Å | A=1-718 |
| 6EZN | EM | 3.3 Å | F=1-718 |
| 7OCI | EM | 3.46 Å | F=1-718 |
| 6C26 | EM | 3.5 Å | A=1-718 |
| 2LGZ | NMR | A=465-718 |
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