P40465: Chromosome segregation in meiosis protein 2 (CSM2)

Chromosome segregation in meiosis protein 2 (CSM2) is a 213-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P40465.

Gene
CSM2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
213 residues
Mean pLDDT
88.6
Model
AF-P40465-F1 v6
Model created
1 Aug 2025
PDB structures
4

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Model confidence (pLDDT)

The mean pLDDT of this model is 88.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate71%
70 to 90Confident: backbone generally right17%
50 to 70Low: treat with caution6%
Below 50Very low: often disordered regions5%

What pLDDT means and how to read it

Function

Involved in chromosome segregation during meiosis. Promotes efficient recombinational repair and functions in the protection of the genome from spontaneous and induced DNA damage like mutations and gross chromosomal rearrangements (GCRs)

Subunit structure

Component of the SHU complex composed of at least CSM2, PSY3, SHU1 and SHU2

Subcellular location

Cytoplasm, Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
3VU9X-ray1.75 ÅB=1-213
4EQ6X-ray1.8 ÅA=1-213
4DT1X-ray1.9 ÅA=1-213
5XYNX-ray3.3 ÅB=1-213

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