P42920: Large ribosomal subunit protein uL3 (rplC)

Large ribosomal subunit protein uL3 (rplC) is a 209-residue protein from Bacillus subtilis (strain 168). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P42920.

Gene
rplC
Organism
Bacillus subtilis (strain 168)
Length
209 residues
Mean pLDDT
92.5
Model
AF-P42920-F1 v6
Model created
1 Aug 2025
PDB structures
37

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Model confidence (pLDDT)

The mean pLDDT of this model is 92.5 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate86%
70 to 90Confident: backbone generally right13%
50 to 70Low: treat with caution1%
Below 50Very low: often disordered regions0%

What pLDDT means and how to read it

Function

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity). Strongly stimulates 23S rRNA precursor processing by mini-ribonuclease 3 (MrnC); 20-30% DMSO can replace L3, suggesting the protein may alter rRNA conformation

Subunit structure

Part of the 50S ribosomal subunit (PubMed:30126986). Forms a cluster with proteins L14 and L19 (By similarity). Interacts with RNA helicase CshA (PubMed:23175651)

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8S1PEM1.96 ÅD=1-209
8QCQEM2.3 ÅD=1-209
9FY1EM2.3 ÅD=1-209
9FY2EM2.3 ÅD=1-209
9FY3EM2.8 ÅD=1-209
7AS8EM2.9 ÅF=1-209
8BUUEM2.9 ÅD=1-209
7AQCEM2.99 ÅD=1-209
7SAEEM3.0 ÅD=1-209
6TNNEM3.07 ÅX=1-209
6TPQEM3.07 ÅX=1-209
6HA1EM3.1 ÅD=1-209
7AQDEM3.1 ÅD=1-209
9BSLEM3.1 ÅD=1-209
9BSSEM3.1 ÅD=1-209
7OPEEM3.2 ÅF=1-209
7S9UEM3.2 ÅD=1-209
9BS0EM3.3 ÅD=1-209
7O5BEM3.33 Åa=1-208
6PPFEM3.4 ÅD=1-209

Showing 20 of 37 experimental structures (best resolution first).

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