Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is a 277-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P43489.
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The mean pLDDT of this model is 77.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 51% |
| 70 to 90 | Confident: backbone generally right | 7% |
| 50 to 70 | Low: treat with caution | 21% |
| Below 50 | Very low: often disordered regions | 21% |
What pLDDT means and how to read it
Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity
Interacts with TRAF2, TRAF3 and TRAF5
Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1D0A | X-ray | 2.0 Å | G/H/I/J/K/L=261-266 |
| 2HEY | X-ray | 2.0 Å | R/T=29-170 |
| 6OKM | X-ray | 2.1 Å | R=29-170 |
| 2HEV | X-ray | 2.41 Å | R=29-170 |
| 7YK4 | X-ray | 2.7 Å | A/B=29-170 |
| 6OGX | X-ray | 2.77 Å | G=29-170 |
| 6OKN | X-ray | 3.25 Å | E/R=29-170 |
| 8AG1 | X-ray | 3.3 Å | A/a=29-170 |
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