P47962: Large ribosomal subunit protein uL18 (Rpl5)

Large ribosomal subunit protein uL18 (Rpl5) is a 297-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P47962.

Gene
Rpl5
Organism
Mus musculus
Length
297 residues
Mean pLDDT
96.5
Model
AF-P47962-F1 v6
Model created
1 Aug 2025
PDB structures
11

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Model confidence (pLDDT)

The mean pLDDT of this model is 96.5 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate98%
70 to 90Confident: backbone generally right1%
50 to 70Low: treat with caution0%
Below 50Very low: often disordered regions0%

What pLDDT means and how to read it

Function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (By similarity). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (By similarity). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic…

Subunit structure

Component of the large ribosomal subunit (LSU) (PubMed:36517592). Part of the 5S RNP complex, which is a LSU subcomplex composed of the 5S RNA, RPL5 and RPL11 (By similarity). Component of a hexameric 5S RNP precursor complex, composed of 5S RNA, RRS1, RPF2/BXDC1, RPL5, RPL11 and HEATR3; this complex acts as a precursor for ribosome assembly (By similarity). Interacts with NVL in an…

Subcellular location

Cytoplasm, Nucleus, nucleolus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9H4NEM2.46 ÅG2=2-294
9QOHEM2.78 ÅG2=1-297
9QQPEM2.8 ÅG2=1-297
7CPUEM2.82 ÅLD=1-297
7CPVEM3.03 ÅLD=1-297
9QQLEM3.09 ÅG2=1-297
6SWAEM3.1 ÅD=4-297
7LS2EM3.1 ÅG2=1-297
9QWTEM3.1 ÅG2=1-297
7LS1EM3.3 ÅG2=1-297
9QSAEM3.4 ÅG2=1-297

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