P48787: Troponin I, cardiac muscle (Tnni3)

Troponin I, cardiac muscle (Tnni3) is a 211-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P48787.

Gene
Tnni3
Organism
Mus musculus
Length
211 residues
Mean pLDDT
78.1
Model
AF-P48787-F1 v6
Model created
1 Aug 2025
PDB structures
23

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Model confidence (pLDDT)

The mean pLDDT of this model is 78.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate42%
70 to 90Confident: backbone generally right16%
50 to 70Low: treat with caution40%
Below 50Very low: often disordered regions2%

What pLDDT means and how to read it

Function

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity

Subunit structure

Interacts with TRIM63 (By similarity). Binds to actin and tropomyosin. Interacts with STK4/MST1 (By similarity)

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9MOWEM4.9 ÅI=1-211
9MOPEM5.0 ÅH=1-211
9MOMEM5.1 ÅI=1-211
9MO7EM5.2 ÅH=1-211
9MO8EM5.2 ÅI=1-211
9MOLEM5.2 ÅI=1-211
9MONEM5.2 ÅI=1-211
9MOOEM5.2 ÅH=1-211
9MOXEM5.2 ÅH=1-211
9MO4EM5.3 ÅH=1-211
9MO5EM5.3 ÅH=1-211
9MO6EM5.3 ÅH=1-211
9MOAEM5.4 ÅH=1-211
9MOIEM5.4 ÅH=1-211
9MOBEM5.5 ÅI=1-211
9MO9EM5.6 ÅH=1-211
9MOCEM5.6 ÅI=1-211
9MOKEM5.6 ÅI=1-211
9MOUEM5.6 ÅI=1-211
9MODEM5.7 ÅI=1-211

Showing 20 of 23 experimental structures (best resolution first).

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