BH3-interacting domain death agonist (BID) is a 195-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P55957.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 63.0 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 0% |
| 70 to 90 | Confident: backbone generally right | 37% |
| 50 to 70 | Low: treat with caution | 45% |
| Below 50 | Very low: often disordered regions | 19% |
What pLDDT means and how to read it
Induces caspases and apoptosis (PubMed:14583606). Counters the protective effect of BCL2 (By similarity)
Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2 (By similarity). Interacts with PLEKHN1 (PubMed:29531808)
Cytoplasm, Mitochondrion membrane, Mitochondrion outer membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7QTW | X-ray | 1.41 Å | B=76-109 |
| 5C3F | X-ray | 1.43 Å | B=80-101 |
| 7M5A | X-ray | 1.5 Å | B=80-100 |
| 5AJJ | X-ray | 1.75 Å | B=79-112 |
| 4ZEQ | X-ray | 1.8 Å | B=79-104 |
| 7M5B | X-ray | 1.85 Å | B/D=80-100 |
| 4QVE | X-ray | 2.05 Å | B=76-109 |
| 4ZII | X-ray | 2.19 Å | C=76-109 |
| 4ZIG | X-ray | 2.2 Å | B=79-98 |
| 4BD2 | X-ray | 2.21 Å | C=76-109 |
| 8SM5 | X-ray | 2.61 Å | B/D/F/H/J=81-98 |
| 7P33 | X-ray | 2.79 Å | F/G/H/I/J=76-109 |
| 1ZY3 | NMR | B=82-101 | |
| 2BID | NMR | A=1-195 | |
| 2KBW | NMR | B=76-106 | |
| 2M5B | NMR | B=80-101 | |
| 2M5I | NMR | A=61-195 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.