Ubiquitin-fold modifier 1 (UFM1) is a 85-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P61960.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 91.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 88% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer (PubMed:15071506, PubMed:20018847, PubMed:27653677, PubMed:29868776, PubMed:30626644, PubMed:38377992, PubMed:38383785). The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1 (PubMed:15071506, PubMed:20018847, PubMed:27653677, PubMed:29868776). Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, transcription or reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress…
Interacts with UBA5 (PubMed:26872069, PubMed:26929408, PubMed:27653677, PubMed:28360427, PubMed:29295865, PubMed:30412706). Interacts with UFC1 (PubMed:29868776)
Nucleus, Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7W3N | X-ray | 1.6 Å | A=1-83 |
| 8BZR | X-ray | 1.78 Å | B=1-83 |
| 5IAA | X-ray | 1.85 Å | C/D=1-83 |
| 5IA7 | X-ray | 2.0 Å | A/B=1-83 |
| 5IA8 | X-ray | 2.0 Å | A/B=3-83 |
| 5L95 | X-ray | 2.1 Å | C/D=4-83 |
| 6H77 | X-ray | 2.1 Å | Q/R/S/T=1-78 |
| 5HKH | X-ray | 2.55 Å | A/C=2-83 |
| 8OJ5 | EM | 2.9 Å | D=1-85 |
| 9GY4 | EM | 3.0 Å | D=1-85 |
| 8OHD | EM | 3.1 Å | D=1-85 |
| 8QFC | EM | 3.2 Å | E=1-83 |
| 8OJ0 | EM | 3.3 Å | D=1-85 |
| 1WXS | NMR | A=1-85 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.