Nuclear transport factor 2 (Nutf2) is a 127-residue protein from Rattus norvegicus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P61972.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 95.0 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 93% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import
Homodimer (PubMed:11846560, PubMed:15522285, PubMed:8757804, PubMed:9533885). Interacts with RAN (GDP-bound form); the interaction is direct and regulates RAN nuclear import (PubMed:11846560, PubMed:15522285, PubMed:8757804, PubMed:9368653, PubMed:9533885, PubMed:9822603). Interacts with the nucleoporins NUP54, NUP58 and NUP62 (via FG repeats); recruits NUTF2 to the nuclear pore complex a step…
Cytoplasm, cytosol, Nucleus outer membrane, Nucleus, nuclear pore complex, Nucleus inner membrane, Nucleus, nucleoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1GY6 | X-ray | 1.6 Å | A/B=1-127 |
| 1JB2 | X-ray | 2.0 Å | A/B=1-127 |
| 1JB4 | X-ray | 2.23 Å | A/B=1-127 |
| 1AR0 | X-ray | 2.3 Å | A/B=1-127 |
| 1ASK | X-ray | 2.3 Å | A/B=1-127 |
| 1JB5 | X-ray | 2.3 Å | A/B=1-127 |
| 1OUN | X-ray | 2.3 Å | A/B=1-127 |
| 1QMA | X-ray | 2.5 Å | A/B/C/D=2-127 |
| 1U5O | X-ray | 2.5 Å | A/B=1-127 |
| 5BXQ | X-ray | 2.5 Å | A/B=1-127 |
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