Actin, alpha skeletal muscle (ACTA1) is a 377-residue protein from Gallus gallus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P68139.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 95.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 92% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 2% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells
Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others
Cytoplasm, cytoskeleton
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7W4Z | X-ray | 1.15 Å | A=1-377 |
| 7W50 | X-ray | 1.15 Å | A=1-377 |
| 7W51 | X-ray | 1.2 Å | A=1-377 |
| 9L2N | X-ray | 1.7 Å | A=3-377 |
| 7W52 | X-ray | 2.0 Å | A/C/E/G=1-377 |
| 1MDU | X-ray | 2.2 Å | B/E=1-377 |
| 8D13 | EM | 2.43 Å | A/B/C=1-377 |
| 8D14 | EM | 2.51 Å | A/B/C=1-377 |
| 7R94 | EM | 2.6 Å | A/B/C/D/E=1-377 |
| 8C4E | EM | 2.6 Å | A/B/C/D/E/F/G/H=1-377 |
| 9JW0 | X-ray | 2.69 Å | B=1-377 |
| 7YNE | X-ray | 2.7 Å | A/C/E/G=1-377 |
| 8C4C | EM | 2.7 Å | A/B/C/D/E/F/G/H=1-377 |
| 8UXW | EM | 2.7 Å | H/I/M/N/O/P/Q/R=1-377 |
| 9JUS | X-ray | 2.7 Å | F/G/P/f/g/p=1-377 |
| 8UZ0 | EM | 2.8 Å | J/K/L/M/N/O/P/Q/R=6-377 |
| 7R8V | EM | 2.82 Å | A/B/C/D/E=7-377 |
| 7R91 | EM | 2.83 Å | A/B/C=7-377 |
| 6UPW | EM | 2.9 Å | A/B/C/D/E=3-377 |
| 9QGK | EM | 2.97 Å | F/G/H/I/J=1-377 |
Showing 20 of 62 experimental structures (best resolution first).
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.