P80162: C-X-C motif chemokine 6 (CXCL6)

C-X-C motif chemokine 6 (CXCL6) is a 114-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P80162.

Gene
CXCL6
Organism
Homo sapiens
Length
114 residues
Mean pLDDT
81.0
Model
AF-P80162-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 81.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate51%
70 to 90Confident: backbone generally right19%
50 to 70Low: treat with caution26%
Below 50Very low: often disordered regions4%

What pLDDT means and how to read it

Function

Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7)

Subcellular location

Secreted

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8XXXEM3.17 ÅD=38-114
8XWMEM3.71 ÅD=38-114

More AlphaFold highlights

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