Actin-related protein 4 (ARP4) is a 489-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P80428.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 85.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 76% |
| 70 to 90 | Confident: backbone generally right | 7% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 14% |
What pLDDT means and how to read it
Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. ARP4 recognizes H2AS128ph (gamma-H2A) and is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes. Its ability to induce transcription of some phosphate-responsive genes is modulated by…
Component of the NuA4 histone acetyltransferase complex composed of at least ACT1, ARP4, EAF3, EAF5, EAF6, EAF7, EPL1, ESA1, SWC4, TRA1, VID21, YAF9 and YNG2. Component of the chromatin-remodeling INO80 complex, at least composed of ARP4, ARP5, ARP8, RVB1, RVB2, TAF14, NHP10, IES1, IES3, IES4, IES6, ACT1, IES2, IES5 and INO80. Component of the SWR1 chromatin remodeling complex composed of at…
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5I9E | X-ray | 2.8 Å | A/C=1-489 |
| 5NBL | X-ray | 2.8 Å | A/B=1-489 |
| 7VVY | EM | 3.1 Å | F=1-489 |
| 8ESC | EM | 3.1 Å | R=1-489 |
| 8A5O | EM | 3.2 Å | W=1-489 |
| 8A5A | EM | 3.3 Å | W=1-489 |
| 3QB0 | X-ray | 3.4 Å | A/B/C/D=1-489 |
| 5NBM | X-ray | 3.4 Å | A/B=1-489 |
| 7YFN | EM | 3.8 Å | B=1-489 |
| 5NBN | X-ray | 4.0 Å | A/B=1-489 |
| 7YFP | EM | 4.0 Å | B=8-488 |
| 5Y81 | EM | 4.7 Å | F=1-489 |
| 7VVZ | EM | 8.8 Å | F=1-489 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.