Q06103: 26S proteasome regulatory subunit RPN7 (RPN7)

26S proteasome regulatory subunit RPN7 (RPN7) is a 429-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q06103.

Gene
RPN7
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
429 residues
Mean pLDDT
82.1
Model
AF-Q06103-F1 v6
Model created
1 Aug 2025
PDB structures
29

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Model confidence (pLDDT)

The mean pLDDT of this model is 82.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate34%
70 to 90Confident: backbone generally right53%
50 to 70Low: treat with caution5%
Below 50Very low: often disordered regions8%

What pLDDT means and how to read it

Function

Component of the 19S cap proteasome complex which acts as a regulatory subunit of the 26S proteasome, involved in the ATP-dependent degradation of ubiquitinated proteins

Subunit structure

The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively. Component of the lid subcomplex of the 19S RC

Subcellular location

Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
3JCKEM3.5 ÅD=1-429
9CGCEM3.61 ÅR=1-429
6J2QEM3.8 ÅR=1-429
6J2XEM3.8 ÅR=1-429
5MPDEM4.1 ÅR=1-429
6FVTEM4.1 ÅR=20-424
5WVKEM4.2 ÅR=1-429
5MPEEM4.5 ÅR=1-429
6FVUEM4.5 ÅR=20-424
6FVWEM4.5 ÅR=20-424
6J30EM4.5 ÅR=1-429
3JCPEM4.6 ÅR=1-429
3JCOEM4.8 ÅR=1-429
6FVXEM4.9 ÅR=20-424
6FVVEM5.4 ÅR=20-424
7QO5EM6.0 ÅR=1-429
6FVYEM6.1 ÅR=20-424
7QO3EM6.1 ÅR=1-429
5WVIEM6.3 ÅR=1-429
6J2CEM7.0 ÅR=1-429

Showing 20 of 29 experimental structures (best resolution first).

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