Alpha/kappa-conotoxin pl14a is a 76-residue protein from Conus planorbis. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q0N4U8.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 64.4 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 0% |
| 70 to 90 | Confident: backbone generally right | 45% |
| 50 to 70 | Low: treat with caution | 28% |
| Below 50 | Very low: often disordered regions | 28% |
What pLDDT means and how to read it
Highly inhibits both nicotinic acetylcholine receptors (neuronal (IC(50)=8.7 uM for alpha-3/beta-4) and muscular (IC(50)=0.54 uM for alpha-1-beta-1-epsilon-delta (CHRNA1-CHRNB1-CHRND-CHRNE)) subtypes) and the voltage-gated potassium channel Kv1.6/KCNA6 subtype (IC(50)=1.59 uM)
Secreted
Compare the prediction with experimentally determined structures of the same protein:
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.