Q12250: 26S proteasome regulatory subunit RPN5 (RPN5)

26S proteasome regulatory subunit RPN5 (RPN5) is a 445-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q12250.

Gene
RPN5
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
445 residues
Mean pLDDT
77.4
Model
AF-Q12250-F1 v6
Model created
1 Aug 2025
PDB structures
30

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Model confidence (pLDDT)

The mean pLDDT of this model is 77.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate6%
70 to 90Confident: backbone generally right75%
50 to 70Low: treat with caution17%
Below 50Very low: often disordered regions3%

What pLDDT means and how to read it

Function

Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
3JCKEM3.5 ÅB=1-445
9CGCEM3.61 ÅP=1-445
6J2QEM3.8 ÅP=1-445
6J2XEM3.8 ÅP=1-445
5MPDEM4.1 ÅP=1-445
6FVTEM4.1 ÅP=1-440
5WVKEM4.2 ÅP=1-445
5MPEEM4.5 ÅP=1-445
6FVUEM4.5 ÅP=1-440
6FVWEM4.5 ÅP=1-440
6J30EM4.5 ÅP=1-445
3JCPEM4.6 ÅP=1-445
3JCOEM4.8 ÅP=1-445
6FVXEM4.9 ÅP=1-440
6FVVEM5.4 ÅP=1-440
7QO5EM6.0 ÅP=1-445
6FVYEM6.1 ÅP=1-440
7QO3EM6.1 ÅP=1-445
5WVIEM6.3 ÅP=1-445
6J2CEM7.0 ÅP=1-445

Showing 20 of 30 experimental structures (best resolution first).

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