Q12432: Chromatin modification-related protein EAF3 (EAF3)

Chromatin modification-related protein EAF3 (EAF3) is a 401-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q12432.

Gene
EAF3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
401 residues
Mean pLDDT
76.4
Model
AF-Q12432-F1 v6
Model created
1 Aug 2025
PDB structures
33

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Model confidence (pLDDT)

The mean pLDDT of this model is 76.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate46%
70 to 90Confident: backbone generally right21%
50 to 70Low: treat with caution8%
Below 50Very low: often disordered regions24%

What pLDDT means and how to read it

Function

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair

Subunit structure

Component of the NuA4 histone acetyltransferase complex composed of at least ACT1, ARP4, YAF9, VID21, SWC4, EAF3, EAF5, EAF6, EAF7, EPL1, ESA1, TRA1 and YNG2

Subcellular location

Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8I3FX-ray1.62 ÅA=218-400
3E9FX-ray1.8 ÅA=1-113
8I3GX-ray2.4 ÅA/B=218-401
3E9GX-ray2.5 ÅA/B=1-124
7YI1EM2.8 ÅK/L=1-401
8TOFEM2.8 ÅD/E=1-401
8KD3EM2.9 ÅD/F=1-401
8KD5EM2.9 ÅD/F=1-401
8KD4EM2.93 ÅD/F=1-401
8HXXEM3.0 ÅM/O=1-401
8KD2EM3.02 ÅD/F=1-401
8KD6EM3.07 ÅD/F=1-401
8KD7EM3.09 ÅD/F=1-401
8HXYEM3.1 ÅM=1-401
8HY0EM3.1 ÅM/O=1-401
7YI0EM3.2 ÅC/E=1-401
7YI3EM3.3 ÅC=1-401
8W9CEM3.3 ÅC/D=1-401
8IHNEM3.37 ÅN/P=1-401
7YI2EM3.4 ÅC=1-401

Showing 20 of 33 experimental structures (best resolution first).

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