Q12769: Nuclear pore complex protein Nup160 (NUP160)

Nuclear pore complex protein Nup160 (NUP160) is a 1436-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q12769.

Gene
NUP160
Organism
Homo sapiens
Length
1436 residues
Mean pLDDT
80.4
Model
AF-Q12769-F1 v6
Model created
1 Aug 2025
PDB structures
4

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Model confidence (pLDDT)

The mean pLDDT of this model is 80.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate21%
70 to 90Confident: backbone generally right62%
50 to 70Low: treat with caution11%
Below 50Very low: often disordered regions7%

What pLDDT means and how to read it

Function

Functions as a component of the nuclear pore complex (NPC) (PubMed:11564755, PubMed:11684705). Involved in poly(A)+ RNA transport

Subunit structure

Part of the nuclear pore complex (NPC) (PubMed:11564755, PubMed:11684705). Forms part of the NUP160 subcomplex in the nuclear pore which is composed of NUP160, NUP133, NUP107 and NUP96 (PubMed:11564755, PubMed:11684705). This complex plays a role in RNA export and in tethering NUP98 and NUP153 to the nucleus (PubMed:11564755, PubMed:11684705)

Subcellular location

Nucleus, nuclear pore complex

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7R5KEM12.0 ÅR0/R1/R2/R3=1-1436
5A9QEM23.0 Å1/J/S/a=1-1436
7PEQEM35.0 ÅAJ/BJ/CJ/DJ=1-1436
7R5JEM50.0 ÅR0/R1/R2/R3=1-1436

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About this viewer

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