Q1EHW4: Histone deacetylase complex subunit SAP25 (Sap25)

Histone deacetylase complex subunit SAP25 (Sap25) is a 186-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q1EHW4.

Gene
Sap25
Organism
Mus musculus
Length
186 residues
Mean pLDDT
57.3
Model
AF-Q1EHW4-F1 v6
Model created
1 Aug 2025
PDB structures
1

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Model confidence (pLDDT)

The mean pLDDT of this model is 57.3 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate7%
70 to 90Confident: backbone generally right11%
50 to 70Low: treat with caution45%
Below 50Very low: often disordered regions38%

What pLDDT means and how to read it

Function

Involved in the transcriptional repression mediated by the mSIN3A but not the N-CoR corepressor complex

Subunit structure

May be a component of the mSIN3A corepressor complex. Interacts with SIN3A and HDAC2

Subcellular location

Nucleus, Cytoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
2RMSNMRB=126-186

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