MHC class II HLA-DQ-alpha chain (HLA-DQA1) is a 227-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: Q30069.
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The mean pLDDT of this model is 91.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 80% |
| 70 to 90 | Confident: backbone generally right | 12% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Endosome membrane, Lysosome membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6DFX | X-ray | 2.03 Å | A/D=3-184 |
| 6XC9 | X-ray | 2.4 Å | A/F=1-184 |
| 8VD0 | X-ray | 2.4 Å | A/F=1-185 |
| 8VCX | X-ray | 2.59 Å | A=1-185 |
| 8VCY | X-ray | 2.6 Å | A=1-184 |
| 8VDD | X-ray | 2.6 Å | A=1-184 |
| 4Z7V | X-ray | 2.65 Å | A/C=1-184 |
| 4Z7U | X-ray | 2.7 Å | A/C=1-184 |
| 4Z7W | X-ray | 2.89 Å | A/C=1-184 |
| 6XCO | X-ray | 2.9 Å | A=1-184 |
| 8VD2 | X-ray | 2.9 Å | A=1-185 |
| 6XCP | X-ray | 3.3 Å | A=1-184 |
| 8VDU | X-ray | 3.5 Å | A/D/G/J=1-184 |
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