Actin-related protein 2/3 complex subunit 1B (ARPC1B) is a 372-residue protein from Bos taurus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q58CQ2.
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The mean pLDDT of this model is 92.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 84% |
| 70 to 90 | Confident: backbone generally right | 7% |
| 50 to 70 | Low: treat with caution | 5% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs)
Component of the Arp2/3 complex composed of ACTR2/ARP2, ACTR3/ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC
Cytoplasm, cytoskeleton, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1K8K | X-ray | 2.0 Å | C=1-372 |
| 2P9I | X-ray | 2.46 Å | C=1-372 |
| 3UKR | X-ray | 2.48 Å | C=1-372 |
| 3ULE | X-ray | 2.5 Å | C=1-372 |
| 1TYQ | X-ray | 2.55 Å | C=1-372 |
| 1U2V | X-ray | 2.55 Å | C=1-372 |
| 2P9K | X-ray | 2.59 Å | C=1-372 |
| 2P9L | X-ray | 2.65 Å | C=1-372 |
| 3RSE | X-ray | 2.65 Å | C=1-372 |
| 2P9S | X-ray | 2.68 Å | C=1-372 |
| 3DXK | X-ray | 2.7 Å | C=1-372 |
| 2P9U | X-ray | 2.75 Å | C=1-372 |
| 3UKU | X-ray | 2.75 Å | C=1-372 |
| 2P9N | X-ray | 2.85 Å | C=1-372 |
| 3DXM | X-ray | 2.85 Å | C=1-372 |
| 2P9P | X-ray | 2.9 Å | C=1-372 |
| 4JD2 | X-ray | 3.08 Å | C=1-372 |
| 7JPN | EM | 3.24 Å | C=1-372 |
| 9M64 | EM | 3.4 Å | C/c=1-372 |
| 9M5E | EM | 3.55 Å | C=1-372 |
Showing 20 of 24 experimental structures (best resolution first).
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