FXYD domain-containing ion transport regulator (FXYD2) is a 65-residue protein from Sus scrofa. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: Q58K79.
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The mean pLDDT of this model is 74.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 39% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 46% |
| Below 50 | Very low: often disordered regions | 5% |
What pLDDT means and how to read it
May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase
Regulatory subunit of the sodium/potassium-transporting ATPase which is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit
Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 3WGU | X-ray | 2.8 Å | E/G=1-65 |
| 3WGV | X-ray | 2.8 Å | E/G=1-65 |
| 8JBK | X-ray | 2.8 Å | E/G=1-65 |
| 7WYT | X-ray | 2.9 Å | E/G=1-65 |
| 8JBM | X-ray | 2.9 Å | E/G=1-65 |
| 8JBL | X-ray | 3.0 Å | E/G=1-65 |
| 7DDL | X-ray | 3.2 Å | E/G=1-65 |
| 7D91 | X-ray | 3.35 Å | G=1-65 |
| 4HYT | X-ray | 3.4 Å | E/G=1-65 |
| 4RES | X-ray | 3.41 Å | E/G=1-65 |
| 7DDH | X-ray | 3.46 Å | E/G=1-65 |
| 3B8E | X-ray | 3.5 Å | G/H=23-51 |
| 3KDP | X-ray | 3.5 Å | G/H=23-49 |
| 7D94 | X-ray | 3.5 Å | E/G=1-65 |
| 7DDK | X-ray | 3.5 Å | E/G=1-65 |
| 7D93 | X-ray | 3.65 Å | E/G=1-65 |
| 7WYS | X-ray | 3.71 Å | E/G=1-65 |
| 7DDI | X-ray | 3.72 Å | E/G=1-65 |
| 9VJ2 | X-ray | 3.79 Å | G=1-65 |
| 7D92 | X-ray | 3.9 Å | G=1-65 |
Showing 20 of 27 experimental structures (best resolution first).
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