Protein phosphatase 1 regulatory subunit 15B (PPP1R15B) is a 713-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q5SWA1.
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The mean pLDDT of this model is 49.0 (very low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 5% |
| 70 to 90 | Confident: backbone generally right | 13% |
| 50 to 70 | Low: treat with caution | 17% |
| Below 50 | Very low: often disordered regions | 65% |
What pLDDT means and how to read it
Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1
Part of a complex containing PPP1R15B, PP1 and NCK1/2 (By similarity). Interacts with PP1
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4V0W | X-ray | 1.55 Å | B/D=631-669 |
| 4V0V | X-ray | 1.61 Å | B/D=631-660 |
| 4V0X | X-ray | 1.85 Å | B=631-684 |
| 9HVF | EM | 3.8 Å | A=411-511 |
| 4V0U | X-ray | 7.88 Å | E/G/I/K/O=631-701 |
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