Q61771: Kinesin-like protein KIF3B (Kif3b)

Kinesin-like protein KIF3B (Kif3b) is a 747-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q61771.

Gene
Kif3b
Organism
Mus musculus
Length
747 residues
Mean pLDDT
75.1
Model
AF-Q61771-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 75.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate27%
70 to 90Confident: backbone generally right44%
50 to 70Low: treat with caution17%
Below 50Very low: often disordered regions13%

What pLDDT means and how to read it

Function

Microtubule-based molecular motor that transport intracellular cargos, such as vesicles, organelles and protein complexes. Uses ATP hydrolysis to generate force to bind and move along the microtubule (PubMed:7559760). Plays a role in cilia formation (PubMed:9865700). Involved in photoreceptor integrity and opsin trafficking in rod photoreceptors (By similarity). Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit GRIN2A into neuronal dendrites (PubMed:31746486)

Subunit structure

Heterodimer of KIF3A and KIF3B (PubMed:7559760). KIF3A/KIF3B heterodimer interacts with KIFAP3 forming a heterotrimeric (KIF3A/KIF3B/KIFAP3) complex (PubMed:8710890). Interacts with the SMC3 subunit of the cohesin complex (By similarity). Interacts directly with IFT20 (PubMed:12821668). Interacts with FLCN (By similarity)

Subcellular location

Cytoplasm, cytoskeleton, Cell projection, cilium, Cell projection, dendritic spine

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9W9HEM2.83 ÅB=475-747
9W9IEM2.9 ÅB=529-747

More AlphaFold highlights

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