Meiosis-specific nuclear structural protein 1 (Mns1) is a 491-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q61884.
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The mean pLDDT of this model is 82.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 35% |
| 70 to 90 | Confident: backbone generally right | 51% |
| 50 to 70 | Low: treat with caution | 9% |
| Below 50 | Very low: often disordered regions | 5% |
What pLDDT means and how to read it
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:37295417, PubMed:37865089, PubMed:37989994). May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis. Required for sperm flagella assembly (PubMed:22396656). May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC). ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules (By similarity)
Able to form oligomers (PubMed:22396656). Microtubule inner protein component of sperm flagellar doublet microtubules (PubMed:37295417, PubMed:37865089, PubMed:37989994). Interacts with ODAD1 (By similarity). Interacts with BBOF1 (PubMed:37198331). Interacts with CFAP65 (PubMed:34231842)
Nucleus, Cytoplasm, cytoskeleton, flagellum axoneme, Cytoplasm, cytoskeleton, cilium axoneme
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8IYJ | EM | 3.5 Å | B/C=1-491 |
| 8I7R | EM | 6.5 Å | A/B=1-491 |
| 8TO0 | EM | 7.7 Å | A/a=1-491 |
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