Q68KK2: Peptidyl-prolyl cis-trans isomerase A

Peptidyl-prolyl cis-trans isomerase A is a 474-residue protein from Aotus trivirgatus. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: Q68KK2.

Organism
Aotus trivirgatus
Length
474 residues
Mean pLDDT
84.4
Model
AF-Q68KK2-F1 v6
Model created
1 Jun 2022
PDB structures
1

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Model confidence (pLDDT)

The mean pLDDT of this model is 84.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate49%
70 to 90Confident: backbone generally right35%
50 to 70Low: treat with caution8%
Below 50Very low: often disordered regions8%

What pLDDT means and how to read it

Subunit structure

Can form homodimers and homotrimers. In addition to lower-order dimerization, also exhibits a higher-order multimerization and both low- and high-order multimerizations are essential for its restriction activity. Interacts with BTBD1 and BTBD2. Interacts with PSMC4, PSMC5, PSMD7 and HSPA8/HSC70. Interacts (via B30.2/SPRY domain) with HSPA1A/B. Interacts with PSMC2, MAP3K7/TAK1, TAB2 and TAB3.…

Subcellular location

Cytoplasm, Secreted

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
5VA4X-ray2.31 ÅA=88-158, A=225-264

More AlphaFold highlights

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