Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Magi1) is a 1471-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q6RHR9.
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The mean pLDDT of this model is 60.1 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 21% |
| 70 to 90 | Confident: backbone generally right | 25% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 49% |
What pLDDT means and how to read it
Plays a role in coupling actin fibers to cell junctions in endothelial cells, via its interaction with AMOTL2 and CDH5 (PubMed:24806444). May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface
Part of a complex composed of AMOTL2, MAGI1 and CDH5, within the complex AMOTL2 acts as a scaffold protein for the interaction of MAGI1 with CDH5 (PubMed:24806444). The complex is required for coupling actin fibers to cell junctions in endothelial cells (PubMed:24806444). Interacts through its WW 2 domain with SYNPO and through its PDZ 5 domain with ACTN4. Interacts with cytoplasmic domain of…
Cytoplasm, Cell membrane, Cell junction, tight junction, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
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