DET1 homolog (DET1) is a 550-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q7L5Y6.
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The mean pLDDT of this model is 89.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 66% |
| 70 to 90 | Confident: backbone generally right | 26% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation
Component of the DCX DET1-COP1 ubiquitin ligase complex at least composed of RBX1, DET1, DDB1, CUL4A and COP1
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9LTJ | EM | 2.65 Å | A=1-550 |
| 9BJZ | EM | 2.83 Å | B=2-550 |
| 9DHD | EM | 2.9 Å | B=12-550 |
| 9LTO | EM | 2.92 Å | B=1-550 |
| 9LTL | EM | 2.93 Å | A=1-550 |
| 9LTR | EM | 3.03 Å | D/H=1-550 |
| 9LTW | EM | 3.25 Å | A=1-550 |
| 9LTZ | EM | 3.26 Å | R=1-550 |
| 9LU1 | EM | 3.62 Å | R=1-550 |
| 9W90 | EM | 3.7 Å | D/H=1-550 |
| 9M0Y | EM | 4.25 Å | R/U=1-550 |
| 9LUL | EM | 4.99 Å | b/e=9-550 |
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