Q8NFN8: Probable G-protein coupled receptor 156 (GPR156)

Probable G-protein coupled receptor 156 (GPR156) is a 814-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q8NFN8.

Gene
GPR156
Organism
Homo sapiens
Length
814 residues
Mean pLDDT
55.5
Model
AF-Q8NFN8-F1 v6
Model created
1 Aug 2025
PDB structures
7

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Model confidence (pLDDT)

The mean pLDDT of this model is 55.5 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate12%
70 to 90Confident: backbone generally right21%
50 to 70Low: treat with caution12%
Below 50Very low: often disordered regions55%

What pLDDT means and how to read it

Function

Orphan G protein-coupled receptor involved in the regulation of hair cell orientation in mechanosensory organs of the inner ear. It is required to trigger a 180 degree reversal in hair cell orientation, creating a virtual line of polarity reversal (LPR) across which stereociliary bundles are arranged in opposite orientations

Subcellular location

Cell membrane

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8YK0EM2.4 ÅA=22-338, B=22-319
8IEPEM2.61 ÅC/D=1-557
8IEIEM2.62 ÅA/B=1-557
8IEQEM2.73 ÅA/B/C/D=1-557
8IEBEM3.03 ÅA/B=1-557
8YJPEM3.09 ÅA/B=1-346
8IEDEM3.33 ÅA/B=1-557

More AlphaFold highlights

About this viewer

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