ASI1-immunoprecipitated protein 3 (AIPP3) is a 587-residue protein from Arabidopsis thaliana. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q8RXT5.
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The mean pLDDT of this model is 69.1 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 25% |
| 70 to 90 | Confident: backbone generally right | 32% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 36% |
What pLDDT means and how to read it
Transcriptional repressor (PubMed:33433058). Together with PHD finger-containing proteins (e.g. PHD1, PAIPP2/PHD2, AIPP2/PHD3, PHD4, PHD5 and PHD6), cooperates to form a BAH-PHD bivalent histone reader complex able to read histone H3 lysine 27 trimethylation (H3K27me3) and low-methylated H3K4 histone marks in order to regulate transcription, especially to prevent early flowering; H3K27me3 reader of this complex (PubMed:33277495, PubMed:33433058). CPL2 is subsequently recruited to form a BAH-PHD-CPL2 complex (BPC) in order to silence several H3K27me3 and low-methylated H3K4 enriched loci, including AGO5, via the phosphorylation state-dependent inhibition of Pol II release from the…
Interacts with MOM1 (PubMed:27113777). Component of the ASI1-AIPP1-EDM2 (AAE) RNA regulatory complex composed of at least AIPP1/EDM3, ASI1 and EDM2 and may contain CPL2, AIPP2 and AIPP3/BDT1 (PubMed:28808009). Part of the BAH-PHD bivalent histone reader complex that contains AIPP2, PAIPP2 and AIPP3/BDT1; the BAH-PHD module associates with CPL2 to form the BAH-PHD-CPL2 complex (BPC) for…
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7CCE | X-ray | 2.4 Å | A=112-279 |
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