Q8TB24: Ras and Rab interactor 3 (RIN3)

Ras and Rab interactor 3 (RIN3) is a 985-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q8TB24.

Gene
RIN3
Organism
Homo sapiens
Length
985 residues
Mean pLDDT
61.4
Model
AF-Q8TB24-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 61.4 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate22%
70 to 90Confident: backbone generally right25%
50 to 70Low: treat with caution5%
Below 50Very low: often disordered regions48%

What pLDDT means and how to read it

Function

Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function

Subunit structure

Interacts with CD2AP, RAB5B, RAB31 and BIN1

Subcellular location

Cytoplasm, Cytoplasmic vesicle, Early endosome

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
3U23X-ray1.11 ÅB=452-467
4WCIX-ray1.65 ÅB/D/F=378-393

More AlphaFold highlights

About this viewer

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