Bcl-2-like protein 2 (BCL2L2) is a 193-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q92843.
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The mean pLDDT of this model is 81.2 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 43% |
| 70 to 90 | Confident: backbone generally right | 38% |
| 50 to 70 | Low: treat with caution | 8% |
| Below 50 | Very low: often disordered regions | 11% |
What pLDDT means and how to read it
Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX
Interacts with HIF3A (via C-terminus domain). Interacts with BOP
Mitochondrion membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4CIM | X-ray | 1.5 Å | A/B=1-163, P/Q=38-58 |
| 2Y6W | X-ray | 2.0 Å | A/B=1-164 |
| 1MK3 | NMR | A=2-171 | |
| 1O0L | NMR | A=1-183 | |
| 1ZY3 | NMR | A=2-171 |
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