U5 small nuclear ribonucleoprotein 40 kDa protein (SNRNP40) is a 357-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q96DI7.
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The mean pLDDT of this model is 85.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 74% |
| 70 to 90 | Confident: backbone generally right | 12% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 13% |
What pLDDT means and how to read it
Required for pre-mRNA splicing as component of the activated spliceosome (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:29301961, PubMed:29360106, PubMed:30315277, PubMed:30705154). Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome (PubMed:16723661, PubMed:26912367, PubMed:9774689). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable)
Component of the pre-catalytic and catalytic spliceosome complexes (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:28781166, PubMed:29301961, PubMed:29360106, PubMed:30315277, PubMed:9731529). Component of the postcatalytic spliceosome P complex (PubMed:30705154). Part of the U5 snRNP complex. Interacts with PRPF8. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and…
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8H6L | EM | 2.6 Å | 5E=1-357 |
| 8H6K | EM | 2.7 Å | 5E=1-357 |
| 8C6J | EM | 2.8 Å | N=1-357 |
| 6ID1 | EM | 2.86 Å | E=1-357 |
| 7DVQ | EM | 2.89 Å | E=1-357 |
| 6ID0 | EM | 2.9 Å | E=1-357 |
| 6QW6 | EM | 2.92 Å | 5O=1-357 |
| 6ICZ | EM | 3.0 Å | E=1-357 |
| 8I0R | EM | 3.0 Å | E=1-357 |
| 8I0T | EM | 3.0 Å | E=1-357 |
| 8I0V | EM | 3.0 Å | E=1-357 |
| 8H6E | EM | 3.2 Å | 5E=1-357 |
| 8Q7Q | EM | 3.2 Å | D=1-357 |
| 8RC0 | EM | 3.2 Å | G=1-357 |
| 8H6J | EM | 3.25 Å | 5E=1-357 |
| 6QX9 | EM | 3.28 Å | 5O=1-357 |
| 6QDV | EM | 3.3 Å | N=51-357 |
| 8I0U | EM | 3.3 Å | E=1-357 |
| 9FMD | EM | 3.3 Å | E=1-357 |
| 8Y6O | EM | 3.38 Å | F=1-357 |
Showing 20 of 53 experimental structures (best resolution first).
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