Ubiquitin-conjugating enzyme E2 E2 (UBE2E2) is a 201-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q96LR5.
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The mean pLDDT of this model is 85.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 74% |
| 70 to 90 | Confident: backbone generally right | 1% |
| 50 to 70 | Low: treat with caution | 12% |
| Below 50 | Very low: often disordered regions | 13% |
What pLDDT means and how to read it
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1Y6L | X-ray | 1.85 Å | A/B/C=55-201 |
| 6W9A | X-ray | 2.3 Å | A/C=30-201 |
| 9BJZ | EM | 2.83 Å | D=2-201 |
| 9LTO | EM | 2.92 Å | A=1-201 |
| 9LTR | EM | 3.03 Å | J/K=1-201 |
| 9LTZ | EM | 3.26 Å | A=1-201 |
| 9LU1 | EM | 3.62 Å | C=1-201 |
| 9W90 | EM | 3.7 Å | J/K=1-201 |
| 9M0Y | EM | 4.25 Å | Q/T=1-201 |
| 9LUL | EM | 4.99 Å | a/d=55-201 |
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