Q99832: T-complex protein 1 subunit eta (CCT7)

T-complex protein 1 subunit eta (CCT7) is a 543-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q99832.

Gene: CCT7
Organism: Homo sapiens
Length: 543 residues
Mean pLDDT: 88.9
Model: AF-Q99832-F1 v6
Model created: 1 Aug 2025
PDB structures: 64

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Model confidence (pLDDT)

The mean pLDDT of this model is 88.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT band	Meaning	Share of residues
Above 90	Very high: backbone and side chains are usually accurate	67%
70 to 90	Confident: backbone generally right	28%
50 to 70	Low: treat with caution	2%
Below 50	Very low: often disordered regions	4%

What pLDDT means and how to read it

Function

Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis (PubMed:25467444, PubMed:36493755, PubMed:35449234, PubMed:37193829). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444)

Subunit structure

Component of the chaperonin-containing T-complex (TRiC), a hexadecamer composed of two identical back-to-back stacked rings enclosing a protein folding chamber (PubMed:25467444, PubMed:36493755, PubMed:35449234, PubMed:37193829). Each ring is made up of eight different subunits: TCP1/CCT1, CCT2, CCT3, CCT4, CCT5, CCT6A/CCT6, CCT7, CCT8 (PubMed:36493755, PubMed:35449234, PubMed:37193829).…

Subcellular location

Cytoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB ID	Method	Resolution	Chains and residues
7NVL	EM	2.5 Å	H/h=1-543
8SH9	EM	2.7 Å	H/h=1-528
8SHE	EM	2.8 Å	H/h=1-528
8SHG	EM	2.8 Å	H/h=1-528
8SHN	EM	2.8 Å	H/h=1-528
7TTT	EM	2.9 Å	C=1-543
8SG9	EM	2.9 Å	H/h=1-528
8SGC	EM	2.9 Å	H/h=1-528
8SGL	EM	2.9 Å	H/h=1-528
8SHD	EM	2.9 Å	H/h=1-528
8SHQ	EM	2.9 Å	H/h=1-528
9NOQ	EM	2.9 Å	H/h=1-543
9NRH	EM	2.9 Å	H/h=1-543
7NVN	EM	3.0 Å	H/h=1-543
7TRG	EM	3.0 Å	C=1-542
8SG8	EM	3.0 Å	H/h=1-528
8SHA	EM	3.0 Å	H/h=1-528
8SHF	EM	3.0 Å	H/h=1-528
8SHL	EM	3.0 Å	H/h=1-528
8SHO	EM	3.0 Å	H/h=1-528

Showing 20 of 64 experimental structures (best resolution first).

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