Q9DB77: Cytochrome b-c1 complex subunit 2, mitochondrial (Uqcrc2)

Cytochrome b-c1 complex subunit 2, mitochondrial (Uqcrc2) is a 453-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9DB77.

Gene
Uqcrc2
Organism
Mus musculus
Length
453 residues
Mean pLDDT
90.7
Model
AF-Q9DB77-F1 v6
Model created
1 Aug 2025
PDB structures
18

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Model confidence (pLDDT)

The mean pLDDT of this model is 90.7 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate82%
70 to 90Confident: backbone generally right11%
50 to 70Low: treat with caution1%
Below 50Very low: often disordered regions6%

What pLDDT means and how to read it

Function

Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation (PubMed:34616041, PubMed:38575788). The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase (PubMed:34616041, PubMed:38575788).…

Subunit structure

Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits (PubMed:34616041, PubMed:38575788). The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6,…

Subcellular location

Mitochondrion inner membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7O3HEM2.6 ÅB/M=15-453
7O37EM3.2 ÅB/M=15-453
7O3CEM3.3 ÅB/M=15-453
8PW6EM3.3 ÅB/M=1-453
8IAREM3.4 ÅAB/Ab=1-453
8IB7EM3.4 ÅAB/Ab=1-453
8PW7EM3.5 ÅB/M=1-453
7O3EEM3.6 ÅB/M=15-453
8IBCEM3.6 ÅAB/Ab=1-453
8PW5EM3.6 ÅB/M=1-453
8UCAEM3.7 Å3B/3M=15-453
8IBGEM3.8 ÅAB/Ab=1-453
8IC5EM4.1 ÅAB/Ab=1-453
8IAOEM4.2 ÅAB/Ab=1-453
8IBDEM4.2 ÅAB/Ab=1-453
8IB4EM4.3 ÅAB/Ab=1-453
8IB9EM4.3 ÅAB/Ab=1-453
8IC2EM6.3 ÅAB/Ab=1-453

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