Q9HBE5: Interleukin-21 receptor (IL21R)

Interleukin-21 receptor (IL21R) is a 538-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9HBE5.

Gene
IL21R
Organism
Homo sapiens
Length
538 residues
Mean pLDDT
64.1
Model
AF-Q9HBE5-F1 v6
Model created
1 Aug 2025
PDB structures
6

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Model confidence (pLDDT)

The mean pLDDT of this model is 64.1 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate33%
70 to 90Confident: backbone generally right9%
50 to 70Low: treat with caution16%
Below 50Very low: often disordered regions42%

What pLDDT means and how to read it

Function

This is a receptor for interleukin-21

Subunit structure

Heterodimer with the common gamma subunit. Associates with JAK1

Subcellular location

Membrane

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
6PLHX-ray1.6 ÅC=202-232
7KQ7X-ray2.2 ÅB=20-233
9E2TX-ray2.28 ÅB/E/H/J=20-228
4NZDX-ray2.75 ÅA/B/C=20-232
3TGXX-ray2.8 ÅA/C/E/G/I/K/M/O=20-232
8ENTX-ray2.83 ÅB/E/H/K=20-229

More AlphaFold highlights

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