Phorbol-12-myristate-13-acetate-induced protein 1 (Pmaip1) is a 103-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9JM54.
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The mean pLDDT of this model is 63.8 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 0% |
| 70 to 90 | Confident: backbone generally right | 33% |
| 50 to 70 | Low: treat with caution | 52% |
| Below 50 | Very low: often disordered regions | 16% |
What pLDDT means and how to read it
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1 (By similarity). Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1
Interacts with MCL1 (PubMed:10807576, PubMed:15694340, PubMed:15901672, PubMed:17389404). Interacts with BCL2A1 (By similarity). Interacts with BAX (By similarity). Interacts with BCL2L10 (By similarity)
Mitochondrion
Compare the prediction with experimentally determined structures of the same protein:
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