Protein HEG homolog 1 (HEG1) is a 1381-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9ULI3.
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The mean pLDDT of this model is 42.3 (very low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 2% |
| 70 to 90 | Confident: backbone generally right | 15% |
| 50 to 70 | Low: treat with caution | 5% |
| Below 50 | Very low: often disordered regions | 78% |
What pLDDT means and how to read it
Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions
Interacts with CCM2 and KRIT1; KRIT1 markedly facilitates interaction with CCM2
Cell membrane, Cell junction, Secreted
Compare the prediction with experimentally determined structures of the same protein:
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