Q9Y266: Nuclear migration protein nudC (NUDC)

Nuclear migration protein nudC (NUDC) is a 331-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q9Y266.

Gene
NUDC
Organism
Homo sapiens
Length
331 residues
Mean pLDDT
81.4
Model
AF-Q9Y266-F1 v6
Model created
1 Aug 2025
PDB structures
2

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Model confidence (pLDDT)

The mean pLDDT of this model is 81.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate49%
70 to 90Confident: backbone generally right29%
50 to 70Low: treat with caution12%
Below 50Very low: often disordered regions11%

What pLDDT means and how to read it

Function

Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis (PubMed:12679384, PubMed:12852857, PubMed:25789526). Necessary for cytokinesis and cell proliferation (PubMed:12679384, PubMed:12852857)

Subunit structure

Interacts with PAFAH1B1 (By similarity). Interacts with PLK1 (PubMed:12852857). Part of a complex containing PLK1, NUDC, dynein and dynactin (PubMed:12852857). Interacts with DCDC1 (PubMed:22159412). Interacts with EML4 (via WD repeats) (PubMed:25789526)

Subcellular location

Cytoplasm, cytoskeleton, Nucleus, Cytoplasm, cytoskeleton, spindle, Midbody

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
3QORX-ray1.75 ÅA/B/C/D/E=158-274
7NDXX-ray2.54 ÅB=100-141

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