IgG H chain is a 466-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: S6B291.
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The mean pLDDT of this model is 86.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 63% |
| 70 to 90 | Confident: backbone generally right | 25% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 5% |
What pLDDT means and how to read it
Cell membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4LLY | X-ray | 1.6 Å | A/C=20-243 |
| 3MNZ | X-ray | 1.8 Å | B=20-241 |
| 6B9Z | X-ray | 1.82 Å | B=20-239 |
| 4LLW | X-ray | 1.95 Å | A/C=20-243 |
| 6BAE | X-ray | 2.14 Å | B=20-239 |
| 3MNW | X-ray | 2.2 Å | B=20-241 |
| 5VEB | X-ray | 2.34 Å | A/H=20-243 |
| 6AU5 | X-ray | 2.48 Å | B/D=20-238 |
| 6AXP | X-ray | 2.48 Å | B/D=20-238 |
| 6AYN | X-ray | 2.48 Å | B/D=20-238 |
| 6AZK | X-ray | 2.48 Å | B/D=20-238 |
| 6AZL | X-ray | 2.48 Å | B/D=20-238 |
| 6VTU | X-ray | 2.61 Å | H=20-237 |
| 4YDV | X-ray | 2.7 Å | B/H=5-241 |
| 5VQM | X-ray | 2.79 Å | D/H=20-239 |
| 6UTE | X-ray | 2.9 Å | A/C/E/G/I=20-243 |
| 5VIC | X-ray | 3.0 Å | H=20-242 |
| 5VIG | X-ray | 3.0 Å | A/H=20-242 |
| 5VOB | X-ray | 3.02 Å | H=1-118, H=122-241 |
| 5VL3 | X-ray | 3.1 Å | A/C/E/H=20-239 |
Showing 20 of 30 experimental structures (best resolution first).
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