IgG H chain is a 275-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: S6C4R2.
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The mean pLDDT of this model is 81.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 59% |
| 70 to 90 | Confident: backbone generally right | 17% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 19% |
What pLDDT means and how to read it
Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked
Cell membrane, Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4PUB | X-ray | 1.75 Å | H=20-244 |
| 4OGY | X-ray | 2.1 Å | H/M=20-244 |
| 4LLU | X-ray | 2.16 Å | A/C=20-249 |
| 4OGX | X-ray | 2.4 Å | H=20-244 |
| 5W1K | X-ray | 3.99 Å | B/G/L/T=20-241 |
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