Structure of T-cell surface glycoprotein CD4. Determined by X-ray diffraction at 2.5 Å resolution. Released 1 Apr 1997.
Explore 1CDJ in 3D Show helices and sheets RCSB PDB PDBe
1CDJ contains 2 α-helices and 22 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 2-7 | 6 | 1 |
| β-strand | 12-14 | 3 | 2 |
| β-strand | 17 | 1 | 3 |
| β-strand | 26-30 | 5 | 1 |
| β-strand | 35-40 | 6 | 1 |
| β-strand | 43-46 | 4 | 1 |
| α-helix | 52-54 | 3 | |
| β-strand | 55-56 | 2 | 2 |
| β-strand | 66 | 1 | 3 |
| β-strand | 69-71 | 3 | 2 |
| α-helix | 76-78 | 3 | |
| β-strand | 80-86 | 7 | 1 |
| β-strand | 89-98 | 10 | 1 |
| β-strand | 99 | 1 | 4 |
| β-strand | 102 | 1 | 5 |
| β-strand | 108 | 1 | 6 |
| β-strand | 116 | 1 | 5 |
| β-strand | 119 | 1 | 4 |
| β-strand | 127-130 | 4 | 7 |
| β-strand | 156 | 1 | 8 |
| β-strand | 159-163 | 5 | 7 |
| β-strand | 166-169 | 4 | 7 |
| β-strand | 173 | 1 | 8 |
| β-strand | 176 | 1 | 6 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| T-cell surface glycoprotein CD4 | A | protein | 178 | Homo sapiens | P01730 (AlphaFold model) |
>1CDJ_1 T-CELL SURFACE GLYCOPROTEIN CD4 (chains A) KKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRS LWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLES PPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIVVLA
Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding. Wu, H., Myszka, D.G., Tendian, S.W. et al. Proc Natl Acad Sci U S A (1996) 93:15030-15035. DOI 10.1073/pnas.93.26.15030 · PubMed
Other PDB entries of the same protein (UniProt P01730 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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