1E8S: Alu domain of the mammalian SRP

Alu domain of the mammalian SRP (potential Alu retroposition intermediate). Determined by X-ray diffraction at 4.0 Å resolution. Released 8 Nov 2000.

Method

X-ray diffraction

Resolution

4.0 Å

Organism

HOMO SAPIENS

Chains

3

Atoms

235

Mol. weight

50.91 kDa

Ligands

EU3

Released

8 Nov 2000

Explore 1E8S in 3D Show helices and sheets RCSB PDB PDBe

Molecules and chains

>1E8S_1 SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN (chains A)
PQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGNLCVKVTDDLVCLVYKTDQAQDVKK
IEKFHSQLMRLMVAKEARNVTMETE

>1E8S_2 SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN (chains B)
VLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPIPKKGTVEGFEPADNKCLLRAT
DGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKTKKTK

>1E8S_3 7SL RNA, 88-MER (chains C)
GCUAGCGAGACCCCGUCUCUGCCGGGCGCGGUGGCGCGCGCCUGUAGUCCCAGCUACUCG
GGAGGCUGAGGUGGGAGGAUCGCUAGUC

Ligands and cofactors

Primary citation

Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle. Weichenrieder, O., Wild, K., Strub, K. et al. Nature (2000) 408:167. DOI 10.1038/35041507 · PubMed

Related structures

Other PDB entries of the same protein (UniProt P49458 (AlphaFold model), which also has an AlphaFold model), best resolution first:

• 5AOX 2.04 Å, Human Alu RNA retrotransposition complex in the ribosome-stalling conformation
• 1E8O 3.2 Å, Core of the Alu domain of the mammalian SRP
• 7NFX 3.2 Å, Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A
• 4UYK 3.22 Å, Crystal structure of a Signal Recognition Particle Alu domain in the elongation arrest…
• 4UYJ 3.35 Å, Crystal structure of a Signal Recognition Particle Alu domain in the elongation arrest…
• 1RY1 12.0 Å, Structure of the signal recognition particle interacting with the elongation-arrested…

Browse structure collections

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