7NFX: UL2
Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A. Determined by electron microscopy at 3.2 Å resolution. Released 2 Jun 2021.
- Method
- Electron microscopy
- Resolution
- 3.2 Å
- Organisms
- Homo sapiens, Oryctolagus cuniculus
- Chains
- 55
- Atoms
- 148,232
- Mol. weight
- 2468.07 kDa
- Ligands
- GNP, GTP, MG, ZN
- Released
- 2 Jun 2021
Explore 7NFX in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7NFX contains 354 α-helices and 330 β-strands across 51 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain a: 9 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-9 | 3 | |
| α-helix | 42-48 | 7 | |
| α-helix | 65-68 | 4 | |
| β-strand | 72-74 | 3 | 10 |
| α-helix | 75-77 | 3 | |
| α-helix | 79-81 | 3 | |
| α-helix | 84-88 | 5 | |
| β-strand | 100-102 | 3 | 11 |
| α-helix | 103-106 | 4 | |
| β-strand | 110-112 | 3 | 10 |
| α-helix | 116-118 | 3 | |
| β-strand | 123-126 | 4 | 11 |
| β-strand | 128-129 | 2 | 10 |
| α-helix | 131-140 | 10 | |
| β-strand | 143-146 | 4 | 11 |
Chain A: 10 helices, 17 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-5 | 3 | |
| α-helix | 9-12 | 4 | |
| α-helix | 29-32 | 4 | |
| α-helix | 34-38 | 5 | |
| β-strand | 40-49 | 10 | 12 |
| α-helix | 57 | 1 | |
| β-strand | 58-64 | 7 | 12 |
| β-strand | 71-77 | 7 | 12 |
| α-helix | 78 | 1 | |
| β-strand | 79 | 1 | 13 |
| β-strand | 83 | 1 | 14 |
| β-strand | 87-91 | 5 | 12 |
| β-strand | 101-103 | 3 | 15 |
| β-strand | 112-114 | 3 | 15 |
| β-strand | 116 | 1 | 16 |
| β-strand | 126 | 1 | 16 |
| β-strand | 134-140 | 7 | 15 |
| α-helix | 142-144 | 3 | |
| β-strand | 145-149 | 5 | 15 |
| β-strand | 155-159 | 5 | 15 |
| β-strand | 163-166 | 4 | 15 |
| α-helix | 168 | 1 | |
| β-strand | 169 | 1 | 13 |
| α-helix | 174-176 | 3 | |
| α-helix | 182-190 | 9 | |
| β-strand | 224-225 | 2 | 17 |
| β-strand | 237-238 | 2 | 17 |
Chain b: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-18 | 7 | |
| α-helix | 37-49 | 13 | |
| α-helix | 54-75 | 22 | |
Chain B: 17 helices, 20 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-10 | 2 | |
| α-helix | 14-16 | 3 | |
| α-helix | 27-28 | 2 | |
| α-helix | 32-36 | 5 | |
| α-helix | 40-41 | 2 | |
| β-strand | 42-43 | 2 | 18 |
| β-strand | 45-59 | 15 | 19 |
| β-strand | 71-80 | 10 | 19 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-95 | 12 | 20 |
| β-strand | 98-106 | 9 | 20 |
| α-helix | 112-117 | 6 | |
| α-helix | 134-138 | 5 | |
| α-helix | 140-156 | 17 | |
| β-strand | 159-165 | 7 | 20 |
| α-helix | 178-179 | 2 | |
| β-strand | 180-184 | 5 | 20 |
| β-strand | 185-186 | 2 | 18 |
| α-helix | 190-199 | 10 | |
| β-strand | 204-205 | 2 | 20 |
| α-helix | 207-210 | 4 | |
| β-strand | 216-222 | 7 | 19 |
| α-helix | 223-225 | 3 | |
| β-strand | 228-229 | 2 | 21 |
| α-helix | 231-234 | 4 | |
| α-helix | 237-241 | 5 | |
| β-strand | 270-271 | 2 | 21 |
| β-strand | 276-288 | 13 | 19 |
| β-strand | 292-293 | 2 | 22 |
| β-strand | 297-298 | 2 | 22 |
| α-helix | 300-303 | 4 | |
| β-strand | 320 | 1 | 23 |
| β-strand | 324 | 1 | 23 |
| β-strand | 330-334 | 5 | 19 |
| β-strand | 344-349 | 6 | 19 |
| β-strand | 365-368 | 4 | 19 |
| α-helix | 382-389 | 8 | |
Chain c: 4 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 14-24 | 11 | |
| β-strand | 26-29 | 4 | 24 |
| α-helix | 32-40 | 9 | |
| β-strand | 45-48 | 4 | 24 |
| α-helix | 54-67 | 14 | |
| β-strand | 70-73 | 4 | 24 |
| α-helix | 78-85 | 8 | |
| β-strand | 93-98 | 6 | 24 |
Chain C: 23 helices, 13 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 7-9 | 3 | 25 |
| β-strand | 10-11 | 2 | 26 |
| β-strand | 12-13 | 2 | 27 |
| β-strand | 15 | 1 | 27 |
| β-strand | 21-23 | 3 | 25 |
| α-helix | 24-25 | 2 | |
| α-helix | 26-29 | 4 | |
| α-helix | 31-32 | 2 | |
| α-helix | 34-44 | 11 | |
| β-strand | 64-66 | 3 | 28 |
| β-strand | 77-79 | 3 | 28 |
| α-helix | 117-130 | 14 | |
| α-helix | 134-139 | 6 | |
| β-strand | 152-154 | 3 | 26 |
| α-helix | 156-158 | 3 | |
| α-helix | 164-173 | 10 | |
| α-helix | 177-186 | 10 | |
| β-strand | 188-189 | 2 | 29 |
| α-helix | 190-191 | 2 | |
| α-helix | 193-195 | 3 | |
| β-strand | 201-202 | 2 | 29 |
| β-strand | 208-211 | 4 | 26 |
| α-helix | 217-220 | 4 | |
| β-strand | 228-231 | 4 | 26 |
| α-helix | 237-240 | 4 | |
| α-helix | 242-244 | 3 | |
| β-strand | 250-253 | 4 | 26 |
| α-helix | 254-264 | 11 | |
| α-helix | 279-282 | 4 | |
| α-helix | 289-293 | 5 | |
| α-helix | 296-299 | 4 | |
| α-helix | 303-305 | 3 | |
| α-helix | 310-314 | 5 | |
| α-helix | 322-328 | 7 | |
| α-helix | 331-337 | 7 | |
| α-helix | 341-362 | 22 | |
Chain d: 5 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 22-28 | 7 | 30 |
| α-helix | 29-33 | 5 | |
| α-helix | 38-40 | 3 | |
| α-helix | 42-56 | 15 | |
| β-strand | 62-64 | 3 | 30 |
| α-helix | 66-72 | 7 | |
| α-helix | 73-75 | 3 | |
| β-strand | 83-90 | 8 | 30 |
| β-strand | 104-108 | 5 | 30 |
Chain D: 17 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 10-15 | 6 | |
| α-helix | 21-25 | 5 | |
| α-helix | 30-37 | 8 | |
| β-strand | 50-55 | 6 | 31 |
| β-strand | 60-66 | 7 | 31 |
| β-strand | 73-79 | 7 | 31 |
| α-helix | 80-82 | 3 | |
| α-helix | 83-86 | 4 | |
| α-helix | 95-113 | 19 | |
| α-helix | 132-135 | 4 | |
| α-helix | 139-142 | 4 | |
| β-strand | 143 | 1 | 32 |
| β-strand | 145-147 | 3 | 31 |
| α-helix | 158-169 | 12 | |
| β-strand | 172 | 1 | 32 |
| β-strand | 181 | 1 | 33 |
| β-strand | 183 | 1 | 33 |
| β-strand | 184 | 1 | 34 |
| β-strand | 189 | 1 | 34 |
| α-helix | 194-199 | 6 | |
| α-helix | 202-214 | 13 | |
| α-helix | 216-222 | 7 | |
| α-helix | 224-227 | 4 | |
| α-helix | 233-235 | 3 | |
| α-helix | 236-249 | 14 | |
| α-helix | 269-272 | 4 | |
| α-helix | 273-291 | 19 | |
43 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Srp RNA 7SL | 1 | RNA | 299 | Homo sapiens | |
| 28S ribosomal RNA | 5 | RNA | 3493 | Oryctolagus cuniculus | |
| 5S ribosomal RNA | 7 | RNA | 120 | Oryctolagus cuniculus | |
| 5.8S ribosomal RNA | 8 | RNA | 156 | Oryctolagus cuniculus | |
| uL2 | A | protein | 245 | Oryctolagus cuniculus | |
| uL3 | B | protein | 403 | Oryctolagus cuniculus | G1TL06 (AlphaFold model) |
| 60S ribosomal protein L4 | C | protein | 413 | Oryctolagus cuniculus | G1SVW5 (AlphaFold model) |
| 60S ribosomal protein L5 | D | protein | 297 | Oryctolagus cuniculus | P19949 (AlphaFold model) |
| 60S ribosomal protein L6 | E | protein | 291 | Oryctolagus cuniculus | G1SKF7 (AlphaFold model) |
| uL30 | F | protein | 225 | Oryctolagus cuniculus | G1SV32 |
| 60S ribosomal protein L7a | G | protein | 319 | Oryctolagus cuniculus | G1STW0 |
| 60S ribosomal protein L9 | H | protein | 192 | Oryctolagus cuniculus | G1SWI6 |
43 more molecules are not listed.
Sequence of entity 1 (1), FASTA
>7NFX_1 SRP RNA 7SL (chains 1)
GCCGGGCGCGGUGGCGCGCGCCUGUAGUCCCAGCUACUCGGGAGGCUGAGGCAGGAGGAU
CGCUUGAGUCCAGGAGUUCUGGGCUGUAGUGCGCUAUGCCGAUCGGGUGUCCGCACUAAG
UUCGGCAUCAAUAUGGUGACCUCCCGGGAGCGGGGGACCACCAGGUUGCCUAAGGAGGGG
UGAACCGGCCCAGGUCGGAAACGGAGCAGGUCAAAACUCCCGUGCUGAUCAGUAGUGGGA
UCGCGCCUGUGAAUAGCCACUGCACUCCAGCCUGGGCAACAUAGCGAGACCCCGUCUCU
Sequence of entity 2 (5), FASTA
>7NFX_2 28S ribosomal RNA (chains 5)
CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAG
AAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGA
AUCCCCGCCCCGCGGCGGGGCGCGGGACAUGUGGCGUACGGAAGACCCGCUCCCCGGCGC
CGCUCGUGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCG
GUAGCGGCCCCCGGCGCGCCGGGCCCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCA
GCCCAAAGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAA
CAAGUACCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAA
CCGUUAAGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGUUCAACCCGGCGGCGGGU
CCGGCCGUGUCGGCGGGUCCCCCGACCGGCGACCGGCCGCCGCCGGGCGCAUUUCCACCG
CGGCGGUGCGCCGCGACCGGCUCCGGGACGGCUGGGAAGGCCCGGCGGGGAAGGUGGCUC
GGCCGAGUGUUACAGCCCCCCCGGCAGCAGCACUCGCCGAAUCCCGGGGCCGAGGGAGCG
AGACCCGUCGCCGCGCUCUCCCCCCUCGGGGGGGCCGGGCCACCCCUCCCACGGCGCGAC
CGCUCGGGGCGGACUGUCCCCAGUGCGCCCCGGGCGGGUCGCGCCGUCGGGCCCGGGGGA
GGGGCCACGCGGCGAGCGCACGGGGUCGGCGGCGACGUCGGCUACCCACCCGACCCGUCU
UGAAACACGGACCAAGGAGUCUAACACGUGCGCGAGUCGGGGGCUCGCACGAAAGCCGCC
GUGGCGCAAUGAAGGUGAAGGCCGGCGCGCUCGCCGGCCGAGGUGGGAUCCCGAGGCCUC
UCCAGUCCGCCGAGGGCGCACCACCGGCCCGUCUCGCCCGCCGCGCCGGGGAGGUGGAGC
ACGAGCGCACGUGUUAGGACCCGAAAGAUGGUGAACUAUGCCUGGGCAGGGCGAAGCCAG
AGGAAACUCUGGUGGAGGUCCGUAGCGGUCCUGACGUGCAAAUCGGUCGUCCGACCUGGG
UAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCCUCCGAAGUUUCCCUCA
GGAUAGCUGGCGCUCUCGCACACGCAGUUUUAUCCGGUAAAGCGAAUGAUUAGAGGUCUU
GGGGCCGAAACGAUCUCAACCUAUUCUCAAACUUUAAAUGGGUAAGAAGCCCGGCUCGCU
GGCGUGAGCCGGGCGUGGAAUGGAGUGCCUAGUGGGCCACUUUUGGUAAGCAGAACUGGC
GCUGCGGGAUGAACCGAACGCCGGGUUAAGGCGCCCGAUGCCGACGCUCAUCAGACCCCA
GAAAAGGUGUUGGUUGAUAUAGAGCCGAAUCAACUAGCCCUGAAAAUGGAUGGCGCUGGA
GCGUCGGGCCCAUACCCGGCCGUCGCCGGCAGUCGAGAGUGGACGGGAGCCCGCCCCCGG
AGCCCCGCGGACGCUACGCCGCGACGAGUAGGAGGGCCGCUGCGGUGAGCCUUGAAGCCU
AGGGCGCGGGCCCGGGUGGAGCCGCCGCAGGUGCAGAUCUUGGUGGUAGUAGCAAAUAUU
CAAACGAGAACUUUGAAGGCCGAAGUGGAGAAGGGUUCCAUGUGAACAGCAGUUGAACAU
GGGUCAGUCGGUCCUGAGAGAUGGGCGAGCGCCGUUCCGAAGGGACGGGCGAUGGCCUCC
GUUGCCCUCGGCCGAUCGAAAGGGAGUCGGGUUCAGAUCCCCGAAUCCGGAGUGGCGGAG
AUGGGCGCCGCGAGGCGUCCAGUGCGGUAACGCGACCGAUCCCGGAGAAGCCGGCGGGAG
CCCCGGGGAGAGUUCUCUUUUCUUUGUGAAGGGCAGGGCGCCCUGGAAUGGGUUCGCCCC
GAGAGAGGGGCCCGUGCCUUGGAAAGCGUCGCGGUUCCGGCGGCGUCCGGUGAGCUCUCG
CUGGCCCUUGAAAAUCCGGGGGAGAGGGUGUAAAUCUCGCGCCGGGCCGUACCCAUAUCC
GCAGCAGGUCUCCAAGGUGAACAGCCUCUGGCAUGUUGGAACAAUGUAGGUAAGGGAAGU
CGGCAAGCCGGAUCCGUAACUUCGGGAUAAGGAUUGGCUCUAAGGGCUGGGUCGGUCGUC
GGCCGGCGCCUAGCAGCCGACUUAGAACUGGUGCGGACCAGGGGAAUCCGACUGUUUAAU
UAAAACAAAGCAUCGCGAAGGCCCGCGGCGGGUGUUGACGCGAUGUGAUUUCUGCCCAGU
GCUCUGAAUGUCAAAGUGAAGAAAUUCAAUGAAGCGCGGGUAAACGGCGGGAGUAACUAU
GACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUGA
ACGAGAUUCCCACUGUCCCUACCUACUAUCCAGCGAAACCACAGCCAAGGGAACGGGCUU
GGCGGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUCUGGCACGGUGAAG
AGACAUGUUUUUUCACUGACCCGGUGAGGCGGGGGGGCGCUCGCUUCUGGCGCCAAGCGC
CCGGCCGCGCGCCGGCCGGGCGCGACCCGCUCCGGGGACAGUGCCAGGUGGGGAGUUUGA
CUGGGGCGGUACACCUGUCAAACGGUAACGCAGGUGUCCUAAGGCGAGCUCAGGGAGGAC
AGAAACCUCCCGUGGAGCAGAAGGGCAAAAGCUCGCUUGAUCUUGAUUUUCAGUACGAAU
ACAGACCGUGAAAGCGGGGCCUCACGAUCCUUCUGACCUUUUGGGUUUUAAGCAGGAGGU
GUCAGAAAAGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUC
GCUUUUUGAUCCUUCGAUGUCGGCUCUUCCUAUCAUUGUGAAGCAGAAUUCACCAAGCGU
UGGAUUGUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUU
AGUUUUACCCUACUGAUGAUGUGUUGUUGCCAUGGUAAUCCUGCUCAGUACGAGAGGAAC
CGCAGGUUCAGACAUUUGGUGUAUGUGCUUGGCUGAGGAGCCAAUGGGGCGAAGCUACCA
UCUGUGGGAUUAUGACUGAACGCCUCUAAGUCAGAAUCCCGCCCAGGCGGAACGAUACGG
CAGCGCCGCGGAGCCUCGGUUGGCCUCGGAUAGCCGGUCCCCCGCGGGGUCCGGUGCGGA
GUGCCCUUCGUCCUGGGAAACGGGGCGCGGCCGGAGAGGCGGCCGCCCCCUCGCCCGUCA
CGCACGCCGUUCGUGGGGAACCUGGCGCUAAACCAUUCGUAGACGACCUGCUUCUGGGUC
GGGGUUUCGUACGUAGCAGAGCAGCUCCCUCGCUGCGAUCUAUUGAAAGUCAGCCCUCGA
CACAAGGGUUUGU
Sequence of entity 3 (7), FASTA
>7NFX_3 5S ribosomal RNA (chains 7)
GUCUACGGCCAUACCACCCUGAACGCGCCCGAUCUCGUCUGAUCUCGGAAGCUAAGCAGG
GUCGGGCCUGGUUAGUACUUGGAUGGGAGACCGCCUGGGAAUACCGGGUGCUGUAGGCUU
Sequence of entity 4 (8), FASTA
>7NFX_4 5.8S ribosomal RNA (chains 8)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCU
Sequence of entity 5 (A), FASTA
>7NFX_5 uL2 (chains A)
MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAK
VVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKP
GDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPIL
KAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAA
RRTGR
Sequence of entity 6 (B), FASTA
>7NFX_6 uL3 (chains B)
MSHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREV
DRPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYK
NWHKSKKKAFTKYCKKWQDDAGKRQLDKDFSSMKKYCQVIRVLAHTQMRLLPLRQKKAHL
MEIQVNGGTVAEKLDWARERLEQQVPVSQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKL
PRKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIK
NNASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRAL
EKIDLKFIDTTSKFGHGRFQTVEEKKAFMGPLKKDRIAKEEGA
Sequence of entity 7 (C), FASTA
>7NFX_7 60S ribosomal protein L4 (chains C)
MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGH
QTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQK
RYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDI
KKVYASQRMRAGKGKMRNRRRIQRRGPCVIYNEDNGIVKAFRNIPGITLLNVTKLNILKL
APGGHVGRFCIWTESAFRKLDDLYGTWRKAASLKSNYNLPMHKMLNTDLSRILKSPEIQR
ALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVERAAAALAA
KSDPKEAPAKKKPVVGKKKKPVVGRKAAAAKKPAADKKAADKRAGPEDKKPAA
Sequence of entity 8 (D), FASTA
>7NFX_8 60S ribosomal protein L5 (chains D)
MGFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDI
ICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYE
GQVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRF
PGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMY
KKAHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES
Sequence of entity 9 (E), FASTA
>7NFX_9 60S ribosomal protein L6 (chains E)
MAGEKAPAAKPDATKKSPAKKADHARGKAKKKTLAEKKPKKGKPHCSRNPVLVRGIGRYS
RSAMYSRKALYKRKYAAPKSRIERKKKREKVLATVTKPVGGDKNGGTRVVKLRKMPRYYP
TEDVPRKLLSHGRKPFSQHVRKLRASITPGTILIILTGRHRGKRVVFLKQLSSGLLLVTG
PLSLNRVPLRRTHQKFVIATSTKIDISGVKIPKHLTDAYFKKKQLRKPRHQEGEIFDTEK
EKYEITEQRKVDQKAVDSQILPKIKAVPQLQGYLRSVFALTNGVYPHKLVF
Sequence of entity 10 (F), FASTA
>7NFX_10 uL30 (chains F)
NFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYV
PAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWG
YPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLGKYGIICMEDLIHEIYTVGKRFKE
ANNFLWPFKLSSPRGGMKKKTTHFVEGEDAGNREDQINRLIRRMN
Sequence of entity 11 (G), FASTA
>7NFX_11 60S ribosomal protein L7a (chains G)
MSSYRLGYCMKEERHNLVLCLWSQSPGILNSKCLWPFTNIHLLVGALPREGAGGAWGGGR
SEQLPTCSTTHHDFTWDKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQR
AILYKRLKVPPAINQFTQVLDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGD
VPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCILKGK
ARLCRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSV
ARIAKLEKAKAKELATKLG
Sequence of entity 12 (H), FASTA
>7NFX_12 60S ribosomal protein L9 (chains H)
MKTILSNQTVDIPENVDISLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKW
WGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGE
KYIRRVRMRPGVACSVSQAQKDELVLEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIY
VSEKGTVQQADE
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| GNP | Phosphoaminophosphonic acid-guanylate ester | C10 H17 N6 O13 P3 | 1 |
| GTP | Guanosine-5'-triphosphate | C10 H16 N5 O14 P3 | 1 |
| MG | Magnesium ion | Mg | 2 |
| ZN | Zinc ion | Zn | 5 |
Primary citation
Receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER. Lee, J.H., Jomaa, A., Chung, S. et al. Sci Adv (2021) 7. DOI 10.1126/sciadv.abg0942 · PubMed
Other PDB entries of the same protein (UniProt G1TL06 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7O7Y 2.2 Å, Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a…
- 7OYD 2.3 Å, Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b
- 11IQ 2.4 Å, Rabbit 80S with eEF2,eIF5A and SERBP1
- 7O7Z 2.4 Å, Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a…
- 8SCB 2.5 Å, Terminating ribosome with SRI-41315
- 9MR4 2.65 Å, NAC: Ribosome nascent chain complex(Oxa1L)
- 9RHU 2.65 Å, Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop codon in mutated F2A…
- 8RJB 2.69 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
- 8VVQ 2.7 Å, Codon sampling state of elongation inhibitor-treated mammalian ribosomes obtained from…
- 8RJD 2.79 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
- 8B6C 2.79 Å, Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative…
- 6SGC 2.8 Å, Rabbit 80S ribosome stalled on a poly(A) tail
Browse structure collections
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