1K83: Yeast RNA Polymerase II

Crystal Structure of Yeast RNA Polymerase II Complexed with the Inhibitor Alpha Amanitin. Determined by X-ray diffraction at 2.8 Å resolution. Released 13 Feb 2002.

Method: X-ray diffraction
Resolution: 2.8 Å
Organisms: SACCHAROMYCES CEREVISIAE, AMANITA PHALLOIDES
Chains: 11
Atoms: 27,902
Mol. weight: 471.14 kDa
Ligands: MN, ZN
Released: 13 Feb 2002

Explore 1K83 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

1K83 contains 166 α-helices and 201 β-strands across 11 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 71 helices, 69 β-strands

Element	Residues	Length	Sheet
α-helix	10	1
β-strand	11	1	1
β-strand	16-18	3	2
β-strand	21	1	3
α-helix	24-30	7
α-helix	80-81	2
β-strand	82	1	4
β-strand	85-91	7	5
α-helix	93-95	3
α-helix	96-103	8
β-strand	106	1	6
β-strand	113	1	6
α-helix	120-127	8
α-helix	133-142	10
β-strand	147	1	7
β-strand	151-153	3	8
β-strand	161-163	3	8
β-strand	170	1	7
α-helix	171-172	2
β-strand	173-177	5	9
β-strand	180-185	6	9
β-strand	198-202	5	9
α-helix	204-211	8
α-helix	216-221	6
β-strand	225	1	10
β-strand	229	1	10
α-helix	231-234	4
β-strand	235-238	4	5
β-strand	241	1	4
α-helix	261-277	17
α-helix	286-304	19
α-helix	325-329	5
β-strand	348-355	8	11
β-strand	363-367	5	11
α-helix	368-371	4
β-strand	375-379	5	12
α-helix	385-394	10
β-strand	402-406	5	12
β-strand	412-414	3	12
β-strand	431-435	5	12
α-helix	436	1
β-strand	441-445	5	11
β-strand	455-463	9	11
β-strand	468-470	3	11
α-helix	472-474	3
α-helix	476-478	3
β-strand	486-490	5	11
α-helix	495-500	6
α-helix	501-505	5
β-strand	506	1	11
α-helix	507-510	4
β-strand	512-513	2	13
β-strand	518-519	2	13
α-helix	525-535	11
β-strand	540-542	3	14
α-helix	543-552	10
α-helix	561-563	3
β-strand	565	1	14
β-strand	571-573	3	14
α-helix	574-581	8
α-helix	583	1
β-strand	588-590	3	15
β-strand	605-607	3	15
β-strand	612-614	3	15
α-helix	619-622	4
α-helix	629-637	9
α-helix	639-660	22
α-helix	666-669	4
α-helix	673-699	27
α-helix	710-736	27
α-helix	742-749	8
α-helix	755-762	8
β-strand	766-767	2	16
β-strand	770	1	17
β-strand	773	1	17
β-strand	779	1	18
β-strand	782	1	18
β-strand	799-800	2	16
α-helix	810-845	36
β-strand	849-850	2	19
β-strand	856-857	2	19
β-strand	863-865	3	19
α-helix	868-870	3
β-strand	873	1	20
α-helix	875-877	3
β-strand	878-882	5	21
α-helix	884-886	3
α-helix	890-897	8
β-strand	913	1	22
α-helix	917-919	3
α-helix	923-946	24
β-strand	953-957	5	21
α-helix	960-970	11
α-helix	978	1
β-strand	979	1	22
α-helix	983-994	12
α-helix	1005-1014	10
α-helix	1016-1025	10
α-helix	1028-1029	2
α-helix	1030-1035	6
α-helix	1039-1055	17
β-strand	1057	1	20
α-helix	1058-1059	2
α-helix	1064-1073	10
α-helix	1075-1077	3
α-helix	1097-1106	10
β-strand	1115-1119	5	23
β-strand	1120	1	24
α-helix	1121	1
α-helix	1122-1124	3
α-helix	1128-1138	11
β-strand	1141-1142	2	25
α-helix	1143-1145	3
β-strand	1147-1154	8	26
α-helix	1164-1166	3
α-helix	1167-1171	5
β-strand	1191-1197	7	26
α-helix	1199-1204	6
α-helix	1209-1217	9
β-strand	1225-1228	4	26
β-strand	1236-1241	6	26
α-helix	1256-1270	15
β-strand	1272-1274	3	25
β-strand	1282-1287	6	23
β-strand	1290-1292	3	27
β-strand	1298-1300	3	27
β-strand	1303-1309	7	23
α-helix	1313-1316	4
β-strand	1322	1	24
β-strand	1328-1329	2	23
α-helix	1332-1338	7
α-helix	1341-1357	17
α-helix	1365-1374	10
β-strand	1378	1	28
α-helix	1406-1414	9
β-strand	1418-1419	2	2
α-helix	1424-1429	6
α-helix	1432-1434	3
α-helix	1437-1439	3
β-strand	1441-1445	5	29

Chain B: 53 helices, 70 β-strands

Element	Residues	Length	Sheet
α-helix	24-25	2
α-helix	27-29	3
α-helix	30-41	12
α-helix	45-53	9
α-helix	54-58	5
α-helix	59-63	5
β-strand	68	1	30
β-strand	91-92	2	30
β-strand	96-100	5	31
β-strand	101-102	2	32
α-helix	108-109	2
β-strand	110-111	2	32
α-helix	114-119	6
β-strand	125-129	5	31
β-strand	132-133	2	30
β-strand	166-171	6	31
α-helix	186-191	6
β-strand	203-205	3	33
β-strand	208-212	5	33
α-helix	213	1
β-strand	214-218	5	34
β-strand	224-227	4	35
β-strand	234-242	9	35
β-strand	252-259	8	35
β-strand	269-272	4	35
β-strand	280-281	2	35
α-helix	282-288	7
α-helix	294-301	8
α-helix	308-320	13
α-helix	327-336	10
α-helix	345-354	10
α-helix	355-359	5
α-helix	371-389	19
α-helix	394-396	3
α-helix	401-403	3
β-strand	404-407	4	34
α-helix	409-428	20
α-helix	451-462	12
β-strand	480-482	3	33
α-helix	483-484	2
α-helix	488-495	8
β-strand	497-499	3	34
α-helix	516-518	3
β-strand	522	1	36
α-helix	530-532	3
β-strand	536-538	3	34
β-strand	539	1	36
β-strand	544-545	2	37
α-helix	552-560	9
β-strand	564-565	2	38
α-helix	566-568	3
α-helix	571-573	3
β-strand	578-582	5	38
β-strand	585-590	6	38
α-helix	594-606	13
β-strand	614-618	5	38
β-strand	623-627	5	38
β-strand	633-639	7	37
β-strand	640-641	2	39
β-strand	650-651	2	39
α-helix	655-666	12
α-helix	681-686	6
β-strand	690-694	5	37
α-helix	695-698	4
β-strand	703-704	2	37
α-helix	707-710	4
α-helix	728-729	2
β-strand	740-741	2	37
α-helix	745-748	4
α-helix	753-755	3
α-helix	759-761	3
α-helix	764-773	10
α-helix	774-776	3
β-strand	777	1	40
β-strand	779	1	41
α-helix	785-787	3
β-strand	792-796	5	41
β-strand	800	1	42
β-strand	804-805	2	43
α-helix	808-812	5
β-strand	821-827	7	44
β-strand	838-842	5	44
α-helix	843-847	5
β-strand	853-861	9	41
β-strand	873-874	2	45
β-strand	898	1	46
β-strand	904	1	41
β-strand	910-912	3	46
β-strand	914-916	3	45
β-strand	935-936	2	45
β-strand	939-940	2	46
α-helix	941-942	2
β-strand	948-956	9	41
β-strand	962-972	11	41
β-strand	979-981	3	44
β-strand	987-994	8	44
β-strand	1001-1002	2	47
β-strand	1010-1012	3	44
α-helix	1014-1016	3
α-helix	1023-1038	16
β-strand	1042-1043	2	43
α-helix	1052-1061	10
β-strand	1069-1070	2	44
β-strand	1072-1073	2	47
α-helix	1079	1
β-strand	1080	1	47
α-helix	1081	1
β-strand	1085-1094	10	44
β-strand	1095	1	40
α-helix	1099-1101	3
β-strand	1105	1	11
α-helix	1132-1140	9
α-helix	1144-1151	8
β-strand	1157-1163	7	1
β-strand	1172-1174	3	48
α-helix	1175-1177	3
β-strand	1179-1181	3	48
β-strand	1182	1	49
β-strand	1187	1	49
β-strand	1191-1197	7	1
α-helix	1198-1209	12
β-strand	1212	1	3
β-strand	1215-1217	3	2

Chain C: 14 helices, 14 β-strands

Element	Residues	Length	Sheet
β-strand	7	1	50
β-strand	17-22	6	51
β-strand	23	1	50
α-helix	27-39	13
β-strand	43-54	12	52
α-helix	60-69	10
β-strand	72	1	53
α-helix	77-79	3
β-strand	96-104	9	52
α-helix	110	1
β-strand	111-114	4	54
α-helix	115-117	3
β-strand	119-120	2	52
α-helix	131	1
β-strand	132	1	53
α-helix	133	1
β-strand	143-147	5	54
β-strand	152-162	11	52
α-helix	168-170	3
β-strand	173-177	5	51
β-strand	180	1	51
α-helix	197-200	4
α-helix	202-204	3
α-helix	205-207	3
α-helix	211-213	3
α-helix	217-219	3
β-strand	228-234	7	51
α-helix	240-264	25

Chain E: 14 helices, 14 β-strands

Element	Residues	Length	Sheet
α-helix	4-26	23
β-strand	28	1	55
α-helix	32-35	4
α-helix	39-46	8
β-strand	47	1	56
β-strand	53	1	56
α-helix	55-57	3
β-strand	60-62	3	57
β-strand	64	1	55
α-helix	66-69	4
β-strand	78-82	5	57
β-strand	87-88	2	58
α-helix	90-102	13
β-strand	107-112	6	57
β-strand	115-116	2	58
α-helix	118-122	5
β-strand	131-136	6	57
α-helix	137-140	4
α-helix	144-146	3
α-helix	151	1
β-strand	152-156	5	28
α-helix	157	1
α-helix	158-167	10
α-helix	172-174	3
β-strand	177-178	2	28
α-helix	183-188	6
β-strand	195-201	7	28
β-strand	207-214	8	28

Chain F: 3 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	84	1	59
α-helix	85-86	2
α-helix	87-102	16
α-helix	117-126	10
β-strand	132-137	6	29
β-strand	143-147	5	29
β-strand	152	1	59

Chain H: 2 helices, 8 β-strands

Element	Residues	Length	Sheet
β-strand	9-16	8	14
β-strand	23-30	8	14
β-strand	37-43	7	14
α-helix	44-46	3
β-strand	54-58	5	14
β-strand	95-101	7	14
β-strand	112-118	7	14
β-strand	121-127	7	14
α-helix	129-132	4
β-strand	140-145	6	14

Chain I: 1 helix, 10 β-strands

Element	Residues	Length	Sheet
β-strand	6	1	60
β-strand	13	1	60
β-strand	15-19	5	61
β-strand	24-28	5	61
β-strand	35-37	3	61
β-strand	42-47	6	26
α-helix	62-64	3
β-strand	70-71	2	62
β-strand	83-87	5	62
β-strand	99-103	5	62
β-strand	109-111	3	62

Chain J: 4 helices, 3 β-strands

Element	Residues	Length	Sheet
β-strand	6	1	63
β-strand	13	1	63
α-helix	18-26	9
α-helix	32-37	6
α-helix	44-51	8
β-strand	53	1	42
α-helix	57-60	4

3 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
DNA-directed RNA polymerase II largest subunit	A	protein	1733	SACCHAROMYCES CEREVISIAE	P04050 (AlphaFold model)
DNA-directed RNA polymerase II 140KD polypeptide	B	protein	1224	SACCHAROMYCES CEREVISIAE	P08518 (AlphaFold model)
DNA-directed RNA polymerase II 45KD polypeptide	C	protein	318	SACCHAROMYCES CEREVISIAE	P16370 (AlphaFold model)
DNA-directed RNA polymerase II 27KD polypeptide	E	protein	215	SACCHAROMYCES CEREVISIAE	P20434 (AlphaFold model)
DNA-directed RNA polymerase II 23KD polypeptide	F	protein	155	SACCHAROMYCES CEREVISIAE	P20435
DNA-directed RNA polymerase II 14.5KD polypeptide	H	protein	146	SACCHAROMYCES CEREVISIAE	P20436
DNA-directed RNA polymerase II 14.2KD polypeptide	I	protein	122	SACCHAROMYCES CEREVISIAE	P27999
DNA-directed RNA polymerase II 8.3KD polypeptide	J	protein	70	SACCHAROMYCES CEREVISIAE	P22139
DNA-directed RNA polymerase II 13.6KD polypeptide	K	protein	120	SACCHAROMYCES CEREVISIAE	P38902
DNA-directed RNA polymerase II 7.7KD polypeptide	L	protein	70	SACCHAROMYCES CEREVISIAE	P40422
Alpha amanitin	M	protein	8	AMANITA PHALLOIDES	P85421

Sequence of entity 1 (A), FASTA

>1K83_1 DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT (chains A)
MVGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMDETQTRAKIGGLNDPRLGS
IDRNLKCQTCQEGMNECPGHFGHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNE
LMRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQLVSRGGCGNTQPTIRKDGLK
LVGSWKKDRATGDADEPELRVLSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLP
VPPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHV
ATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLE
LDQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKR
AGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNA
DFDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTF
IELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSP
KDNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHN
GFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVR
FLNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFV
DRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRR
LVKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVD
LLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNI
RRIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCC
LLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMT
LNTFHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEH
TTLKSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLLDEEAEQSFDQQSPWLLRLELDRA
AMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPKSLDAETEAEEDHML
KKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVP
GIDPTRIYTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGG
LTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDDCRGVSENVILGQMAPIGTGA
FDVMIDEESLVKYMPEQKITEIEDGQDGGVTPYSNESGLVNADLDVKDELMFSPLVDSGS
NDAMAGGFTAYGGADYGEATSPFGAYGEAPTSPGFGVSSPGFSPTSPTYSPTSPAYSPTS
PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS
PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPAYSPTSPSYSPTSPSYSPTSP
SYSPTSPSYSPTSPNYSPTSPSYSPTSPGYSPGSPAYSPKQDEQKHNENENSR

Sequence of entity 2 (B), FASTA

>1K83_2 DNA-DIRECTED RNA POLYMERASE II 140KD POLYPEPTIDE (chains B)
MSDLANSEKYYDEDPYGFEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTLQ
DIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTKPMVNESDGVTHALYPQEARLR
NLTYSSGLFVDVKKRTYEAIDVPGRELKYELIAEESEDDSESGKVFIGRLPIMLRSKNCY
LSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKAAPSPISHVAEI
RSALEKGSRFISTLQVKLYGREGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEH
ICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQYAKDILQKEF
LPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTL
FKKLTKDIFRYMQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKKAMSSRAGVS
QVLNRYTYSSTLSHLRRTNTPIGRDGKLAKPRQLHNTHWGLVCPAETPEGQACGLVKNLS
LMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETL
RTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVRKGHIAK
LMATEYQDIEGGFEDVEEYTWSSLLNEGLVEYIDAEEEESILIAMQPEDLEPAEANEEND
LDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGV
FLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSGYNQEDSMI
MNQSSIDRGLFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIA
PGVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVTTNQDG
LKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSR
MTVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHTGKK
LMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIA
HGAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAA
KLLFQELMAMNITPRLYTDRSRDF

Sequence of entity 3 (C), FASTA

>1K83_3 DNA-DIRECTED RNA POLYMERASE II 45KD POLYPEPTIDE (chains C)
MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD
EFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI
VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY
DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV
DQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPY
SNASQMGNTGSGGYDNAW

Sequence of entity 4 (E), FASTA

>1K83_4 DNA-DIRECTED RNA POLYMERASE II 27KD POLYPEPTIDE (chains E)
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSF
QANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSA
MKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQR
ADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Sequence of entity 5 (F), FASTA

>1K83_5 DNA-DIRECTED RNA POLYMERASE II 23KD POLYPEPTIDE (chains F)
MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQ
HEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRI
AMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Sequence of entity 6 (H), FASTA

>1K83_6 DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE (chains H)
MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIA
SSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGG
LLMRLEGNYRNLNNLKQENAYLLIRR

Sequence of entity 7 (I), FASTA

>1K83_7 DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE (chains I)
MTTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSPLVYRHELITNIGETAGVVQ
DIGSDPTLPRSDRECPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQKNKRTQ
FS

Sequence of entity 8 (J), FASTA

>1K83_8 DNA-DIRECTED RNA POLYMERASE II 8.3KD POLYPEPTIDE (chains J)
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKF
LRYNPLEKRD

Sequence of entity 9 (K), FASTA

>1K83_9 DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE (chains K)
MNAPDRFELFLLGEGESKLKIDPDTKAPNAVVITFEKEDHTLGNLIRAELLNDRKVLFAA
YKVEHPFFARFKLRIQTTEGYDPKDALKNACNSIINKLGALKTNFETEWNLQTLAADDAF

Sequence of entity 10 (L), FASTA

>1K83_10 DNA-DIRECTED RNA POLYMERASE II 7.7KD POLYPEPTIDE (chains L)
MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKAR
TKRLVQFEAR

Sequence of entity 11 (M), FASTA

>1K83_11 ALPHA AMANITIN (chains M)
IWGIGCNP

Ligands and cofactors

ID	Name	Formula	Copies
MN	Manganese (II) ion	Mn	1
ZN	Zinc ion	Zn	8

Primary citation

Structural Basis of Transcription: Alpha-Amanitin-RNA Polymerase II Cocrystal at 2.8 A Resolution. Bushnell, D.A., Cramer, P., Kornberg, R.D. Proc Natl Acad Sci U S A (2002) 99:1218. DOI 10.1073/PNAS.251664698 · PubMed

Other PDB entries of the same protein (UniProt P04050 (AlphaFold model), which also has an AlphaFold model), best resolution first:

5VKO 1.8 Å, SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493
9SV6 1.96 Å, CryoEM structure of transcribing RNA polymerase II elongation complex with ATP and Elf1
5VKL 2.2 Å, SPT6 tSH2-RPB1 1476-1500 pS1493
9W8V 2.23 Å, Structure of post-translocation state of yeast Pol II complexed with a cisplatin-induced…
9QEB 2.26 Å, CryoEM structure of transcribing RNA polymerase II elongation complex
1TWF 2.3 Å, RNA polymerase II complexed with UTP at 2.3 A resolution
9RYB 2.33 Å, CryoEM structure of transcribing RNA polymerase II elongation complex in post-catalysis…
9KD8 2.46 Å, The structure of RNA polymerase II elongation complex paused at N-2 state by actinomycin…
6NPW 2.49 Å, SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide
9K7F 2.5 Å, RNA polymerase II elongation complex apo structure.
30ES 2.54 Å, Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in…
30EP 2.55 Å, Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in…

Browse structure collections

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