Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3. Determined by X-ray diffraction at 2.15 Å resolution. Released 27 Feb 2002.
Explore 1KTZ in 3D Show helices and sheets RCSB PDB PDBe
1KTZ contains 2 α-helices and 21 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 16-18 | 3 | 1 |
| β-strand | 21-23 | 3 | 2 |
| α-helix | 24-28 | 5 | |
| β-strand | 33-35 | 3 | 3 |
| β-strand | 38-40 | 3 | 2 |
| β-strand | 43-45 | 3 | 1 |
| β-strand | 78-80 | 3 | 4 |
| β-strand | 83-92 | 10 | 3 |
| β-strand | 95-106 | 12 | 3 |
| β-strand | 109-111 | 3 | 4 |
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 27-29 | 3 | 3 |
| β-strand | 32-35 | 4 | 5 |
| β-strand | 43-45 | 3 | 6 |
| β-strand | 51-53 | 3 | 3 |
| β-strand | 60-67 | 8 | 5 |
| β-strand | 72-79 | 8 | 5 |
| β-strand | 85 | 1 | 7 |
| β-strand | 88 | 1 | 7 |
| β-strand | 98-100 | 3 | 6 |
| β-strand | 101-103 | 3 | 5 |
| β-strand | 109-115 | 7 | 5 |
| α-helix | 120-122 | 3 | |
| β-strand | 123-126 | 4 | 6 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Transforming growth factor beta 3 | A | protein | 112 | Homo sapiens | P10600 (AlphaFold model) |
| TGF-beta Type II Receptor | B | protein | 122 | Homo sapiens | P37173 (AlphaFold model) |
>1KTZ_1 TRANSFORMING GROWTH FACTOR BETA 3 (chains A) ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
>1KTZ_2 TGF-beta Type II Receptor (chains B) VTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITL ETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSN PD
Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex. Hart, P.J., Deep, S., Taylor, A.B. et al. Nat Struct Biol (2002) 9:203-208. PubMed
Other PDB entries of the same protein (UniProt P10600 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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