Human transforming growth factor beta 3, crystallized from peg 4000. Determined by X-ray diffraction at 3.3 Å resolution. Released 12 Mar 1997.
Explore 1TGK in 3D Show helices and sheets RCSB PDB PDBe
1TGK contains 3 α-helices and 9 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 3 | 1 | 1 |
| α-helix | 4-9 | 6 | |
| β-strand | 16-18 | 3 | 2 |
| β-strand | 22-23 | 2 | 3 |
| β-strand | 35 | 1 | 1 |
| β-strand | 38-39 | 2 | 3 |
| β-strand | 43-45 | 3 | 2 |
| β-strand | 54 | 1 | 1 |
| α-helix | 57-67 | 11 | |
| α-helix | 70-72 | 3 | |
| β-strand | 78-91 | 14 | 1 |
| β-strand | 96-111 | 16 | 1 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Transforming growth factor beta 3 | A | protein | 112 | Homo sapiens | P10600 (AlphaFold model) |
>1TGK_1 TRANSFORMING GROWTH FACTOR BETA 3 (chains A) ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding. Mittl, P.R., Priestle, J.P., Cox, D.A. et al. Protein Sci (1996) 5:1261-1271. PubMed
Other PDB entries of the same protein (UniProt P10600 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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